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54913 RPP25

54913

RPP25

ribonuclease P and MRP subunit p25

protein-coding

Homo sapiens

基因描述

Type Description
Definition ribonuclease P and MRP subunit p25

研究结论

Date Results Publications
2020-12-05 13:04:00 LINC00319 promotes migration, invasion and epithelial-mesenchymal transition process in cervical cancer by regulating miR-3127-5p/RPP25 axis. 31942724
2019-05-18 12:18:00 Study showed the crystal structure of Rpp20/Rpp25 complex, and confirmed that Rpp20 and Rpp25 exhibit similar molecular structures to one another, to their yeast homologs (Pop7 andPop6, respectively), and to archaeal Alba proteins. These proteins do not seem to undergo significant conformational change upon RNA binding, suggesting that they interact with their cognate RNAs via a pre-formed binding surface. 29625199
2015-06-06 13:02:00 Rpp25 is a major target of autoantibodies to the Th/To autoantigen complex 23587095
2011-01-15 11:16:00 Taken together, these findings suggest a potential role for the RPP25 gene transcript in the neurobiology of developmental brain disorders. 20632321
2010-08-02 11:07:00 analyses of interactions with deletion mutant proteins indicate that the Alba-type core domain of both Rpp20 and Rpp25 contains most of the determinants for mutual association and P3 RNA recognition. 20215441

名称对应

Type IDs
Gene
UniProtKB-ID: RPP25_HUMAN
UniprotKB: Q9BUL9
UniParc: UPI0000072730
EMBL: BC002497, AK000381, AY034074, BC007270, CH471136
Ensembl: ENSG00000178718
KO: hsa:54913
Nucleutide sequences
EMBL-CDS: EAW99286.1, AAH02497.1, EAW99285.1, AAH07270.1, BAA91128.1, AAK54443.1
Ensembl_TRS: ENST00000322177
Protein sequencees
Ensembl_PRO: ENSP00000317691
RefSeq: NP_060263.2
Others
UniRef100: UniRef100_Q9BUL9
UniRef90: UniRef90_Q9BUL9
UniRef50: UniRef50_Q9BUL9
UniGene: Hs.8562
CCDS: CCDS10274.1

全选

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研究热度

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