| Type | Description |
|---|---|
| Definition | PX domain containing serine/threonine kinase like |
| Date | Results | Publications |
|---|---|---|
| 2017-02-21 08:57:00 | First described as part of human kinome analysis, named Slob after Drosophila ortholog. | 15289607 |
| 2016-01-02 11:00:00 | Two of these kinases that were classified as resistors were PX domain-containing serine/threonine kinase (PXK) and AP2-associated kinase 1 (AAK1), which promote receptor endocytosis and may enable cells to resist TRAIL-induced apoptosis | 25852190 |
| 2015-12-05 11:20:00 | genetic association study in Han population in China: Data suggest an SNP in PXK [rs2176082(C/T); but not rs6445975(G/T)] is associated with recurrent pregnancy loss; SNPs in KIAA0319L [rs2275247(A/G)] or JAZF1 [rs1635852(C/T)] are not associated. | 25596907 |
| 2015-05-16 12:13:00 | Results confirm the genetic association of the locus 3p14.3 with systemic lupus erythematosus in Europeans and point to the ABHD6 and not PXK, as the major susceptibility gene in the region. | 24534757 |
| 2014-03-22 10:37:00 | study determined that the previously described systemic lupus erythematosus susceptibility loci PXK (P = 3.27 x 10(-11), OR = 1.20) and JAZF1 (P = 1.11 x 10(-8), OR = 1.13) are shared with systemic sclerosis | 23740937 |
| Type | IDs |
|---|---|
| Synonymous | MONAKA, SLOB |
| Gene |
UniProtKB-ID:
PXK_HUMAN,
E9PD56_HUMAN,
B4DJS8_HUMAN,
A0A0C4DG95_HUMAN,
B4DJD8_HUMAN,
W5RX72_HUMAN,
B4DID9_HUMAN
UniprotKB:
Q7Z7A4,
E9PD56,
B4DJS8,
A0A0C4DG95,
B4DJD8,
W5RX72,
B4DID9
UniParc:
UPI00017A71E0,
UPI000020AE18,
UPI000004A035,
UPI000387D6DC,
UPI00017A72DC,
UPI00005D2C11,
UPI00005D2C13,
UPI00005EE279,
UPI00017A7334,
UPI00005EE278,
UPI00005D2C12,
UPI000035E7A7,
UPI0001B794CF
EMBL:
BC008943,
AY847221,
AC135507,
DQ124708,
BC014479,
AY847222,
AF399753,
AY437879,
AB209688,
AK131385,
KF774203,
AK296034,
AK295542,
AC098479,
AK000342,
DQ124707,
AY847220,
AY274811,
AK296215
Ensembl:
ENSG00000168297
KO:
hsa:54899
|
| Nucleutide sequences |
EMBL-CDS:
AAP42076.1,
BAD92925.1,
AAH08943.1,
AAX73354.1,
AAZ38822.1,
AAK94455.1,
BAA91097.1,
AAH14479.1,
AAZ38821.1,
AAX73353.1,
BAD18536.1,
AAR98521.1,
AAX73352.1,
BAG58940.1,
BAG58800.1,
AHG94945.1,
BAG58451.1
Ensembl_TRS:
ENST00000484288,
ENST00000383716,
ENST00000356151,
ENST00000463280,
ENST00000479241
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000417915,
ENSP00000348472,
ENSP00000373222,
ENSP00000417903,
ENSP00000419049
RefSeq:
NP_001336437.1,
XP_016862172.1,
NP_001336458.1,
NP_001336435.1,
NP_001336457.1,
NP_001336455.1,
NP_001336424.1,
NP_001336430.1,
NP_001336469.1,
NP_001276025.1,
NP_001336443.1,
NP_001336447.1,
NP_001336432.1,
NP_001336428.1,
NP_001336462.1,
NP_001336425.1,
NP_001336451.1,
NP_001336427.1,
NP_001336466.1,
NP_001336464.1,
NP_001336467.1,
NP_001276030.1,
NP_001336436.1,
NP_001276024.1,
NP_001336461.1,
NP_001336446.1,
NP_001276027.1,
NP_001336459.1,
NP_001276029.1,
NP_001336445.1,
NP_001336448.1,
NP_001336468.1,
NP_001336442.1,
NP_001336441.1,
XP_005265307.1,
NP_001336465.1,
NP_001336456.1,
NP_001336444.1,
NP_001336426.1,
NP_001336439.1,
NP_001336419.1,
NP_001336421.1,
NP_001336429.1,
NP_001336450.1,
NP_001336438.1,
NP_001336417.1,
NP_001336420.1,
NP_001336460.1,
NP_001276028.1,
NP_060241.2,
NP_001336418.1,
NP_001336433.1,
NP_001336423.1,
XP_016862167.1,
NP_001336463.1,
NP_001336449.1,
NP_001336454.1,
NP_001336440.1,
NP_001336431.1,
NP_001336422.1,
NP_001336453.1
|
| Others |
UniRef100:
UniRef100_A0A0C4DG95,
UniRef100_B4DJS8,
UniRef100_W5RX72,
UniRef100_B4DJD8,
UniRef100_E9PD56,
UniRef100_B4DID9,
UniRef100_Q7Z7A4
UniRef90:
UniRef90_Q7Z7A4,
UniRef90_B4DJD8,
UniRef90_W5RX72,
UniRef90_B4DJS8,
UniRef90_A0A0C4DG95,
UniRef90_E9PD56
UniRef50:
UniRef50_A0A553RHE1,
UniRef50_Q7Z7A4,
UniRef50_Q8BX57-3,
UniRef50_A0A2I3S9L0
UniGene:
Hs.190544
CCDS:
CCDS74952.1,
CCDS2889.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员