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54894 RNF43

54894

RNF43

ring finger protein 43

protein-coding

Homo sapiens

基因描述

Type Description
Definition ring finger protein 43

研究结论

Date Results Publications
2021-04-13 10:09:00 The Functional Landscape of Patient-Derived RNF43 Mutations Predicts Sensitivity to Wnt Inhibition. 33067269
2021-04-13 10:08:00 RNF43 truncations trap CK1 to drive niche-independent self-renewal in cancer. 32965059
2020-11-28 13:11:00 Commonly observed RNF43 mutations retain functionality in attenuating Wnt/beta-catenin signaling and unlikely confer Wnt-dependency onto colorectal cancers. 32103169
2020-11-21 13:35:00 The most common RNF43 mutant G659Vfs*41 is fully functional in inhibiting Wnt signaling and unlikely to play a role in tumorigenesis. 31811196
2020-10-24 14:08:00 RNF43 mutation is associated with aggressive tumor biology along with BRAF V600E mutation in right-sided colorectal cancer. 32236609

名称对应

Type IDs
Synonymous RNF124, SSPCS, URCC
Gene
UniProtKB-ID: RNF43_HUMAN, J3KSE3_HUMAN
UniprotKB: Q68DV7, J3KSE3
UniParc: UPI000268B219, UPI0001A336B5, UPI0001A336B7, UPI000022A469, UPI0001A336B6
EMBL: AK000322, AK291027, CR749257, AK299024, CR627423, BC109028, AC004687, AC023992, AK296769, AB081837, AK298789
Ensembl: ENSG00000108375
KO: hsa:54894
Nucleutide sequences
EMBL-CDS: BAD51435.1, BAH12429.1, BAF83716.1, AAI09029.1, CAH18113.1, BAH12931.1, BAH12871.1, BAA91085.1, CAH10510.1
Ensembl_TRS: ENST00000584437, ENST00000583753, ENST00000407977, ENST00000577625, ENST00000577716, ENST00000581868
Protein sequencees
Ensembl_PRO: ENSP00000462764, ENSP00000385328, ENSP00000463069, ENSP00000462502, ENSP00000463716, ENSP00000462447
RefSeq: NP_001292473.1, NP_060233.3, XP_016880289.1, NP_001292474.1, XP_011523257.1, XP_011523258.1
Others
UniRef100: UniRef100_Q68DV7, UniRef100_J3KSE3
UniRef90: UniRef90_Q68DV7
UniRef50: UniRef50_Q68DV7
UniGene: Hs.584916
CCDS: CCDS11607.1, CCDS82172.1

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