| Type | Description |
|---|---|
| Definition | terminal nucleotidyltransferase 5C |
| Date | Results | Publications |
|---|---|---|
| 2021-02-06 13:59:00 | FAM46C and FNDC3A Are Multiple Myeloma Tumor Suppressors That Act in Concert to Impair Clearing of Protein Aggregates and Autophagy. | 32963011 |
| 2020-11-21 13:14:00 | Down-regulation of miR-10b represses cell vitality in osteosarcoma and is inversely associated with prognosis via interacting with FAM46C: Running title: MiR-10b/FAM46C axis modulates OS progression. | 32223957 |
| 2020-06-06 12:34:00 | Disruption of the family with sequence similarity 46, member C (FAM46C) gene promotes tumorigenicity of myeloma cells. Levels of phosphorylated Akt and its substrates increase both in vitro and in vivo in the FAM46C(-/-) cells compared to WT cells. Loss of FAM46C significantly activated serum-responsive genes while inactivating phosphatase and tensin homolog (PTEN)-related genes. | 32176823 |
| 2019-07-06 12:02:00 | Low FAM46C expression is associated with myocardial dysfunction. | 30910647 |
| 2018-09-01 11:39:00 | Study shows that FAM46C, a tumor suppressor for hepatocellular carcinoma, is important for the anti-proliferation and proapoptotic effects of norcantharidin. | 28341836 |
| Type | IDs |
|---|---|
| Synonymous | FAM46C |
| Gene |
UniProtKB-ID:
TET5C_HUMAN
UniprotKB:
Q5VWP2
UniParc:
UPI0000070C6C
EMBL:
BC131726,
AK000209,
AL365331,
BC036516
Ensembl:
ENSG00000183508
KO:
hsa:54855
|
| Nucleutide sequences |
EMBL-CDS:
BAA91010.1,
AAI31727.1,
AAH36516.3
Ensembl_TRS:
ENST00000369448
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000358458
RefSeq:
NP_060179.2
|
| Others |
UniRef100:
UniRef100_Q5VWP2
UniRef90:
UniRef90_Q5VWP2
UniRef50:
UniRef50_Q5VWP2
UniGene:
Hs.356216
CCDS:
CCDS896.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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