| Type | Description |
|---|---|
| Definition | bestrophin 2 |
| Date | Results | Publications |
|---|---|---|
| 2014-08-23 12:01:00 | BEST2 and BEST4 could be added to the lineage-specific genes of humans intestinal epithelial cells | 24223998 |
| 2012-04-26 16:08:00 | A protein encoded by this locus was found to be differentially expressed in postmortem brains from patients with atypical frontotemporal lobar degeneration. | 22360420 |
| 2010-05-31 11:37:00 | Bestrophin-2 mediates bicarbonate transport by goblet cells in mouse colon | 20407206 |
| 2010-03-15 12:22:00 | These data suggest that Best2 may play a functional role in the regulation of aqueous flow and drainage in humans. | 20157619 |
| 2010-01-21 00:00:00 | Results provide evidence that the bestrophins are expressed in pancreatic duct cells and, more specifically, that hBest1 plays a role in the calcium activated chloride channels found in these cells. | 19237432 |
| Type | IDs |
|---|---|
| Synonymous | VMD2L1 |
| Gene |
UniProtKB-ID:
BEST2_HUMAN
UniprotKB:
Q8NFU1
UniParc:
UPI000007395A
EMBL:
AY515705,
AK000139,
AF440756
Ensembl:
ENSG00000039987
KO:
hsa:54831
|
| Nucleutide sequences |
EMBL-CDS:
BAA90970.1,
AAR99655.1,
AAM76995.1
Ensembl_TRS:
ENST00000549706,
ENST00000553030,
ENST00000042931
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000447203,
ENSP00000042931,
ENSP00000448310
RefSeq:
NP_060152.2
|
| Others |
UniRef100:
UniRef100_Q8NFU1
UniRef90:
UniRef90_Q8NFU1
UniRef50:
UniRef50_Q8NFU1
UniGene:
Hs.435611
CCDS:
CCDS42506.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 32296183 |
A reference map of the human binary protein interactome. Nature Katja Luck , Dae-Kyum Kim , Luke Lambourne , Kerstin Spirohn , Bridget E Begg , Wenting Bian , Ruth Brignall , Tiziana Cafarelli , Francisco J Campos-Laborie , Benoit Charloteaux , Dongsic Choi , Atina G Coté , Meaghan Daley , Steven Deimling , Alice Desbuleux , Amélie Dricot , Marinella Gebbia , Madeleine F Hardy , Nishka Kishore , Jennifer J Knapp , István A Kovács , Irma Lemmens , Miles W Mee , Joseph C Mellor , Carl Pollis , Carles Pons , Aaron D Richardson , Sadie Schlabach , Bridget Teeking , Anupama Yadav , Mariana Babor , Dawit Balcha , Omer Basha , Christian Bowman-Colin , Suet-Feung Chin , Soon Gang Choi , Claudia Colabella , Georges Coppin , Cassandra D'Amata , David De Ridder , Steffi De Rouck , Miquel Duran-Frigola , Hanane Ennajdaoui , Florian Goebels , Liana Goehring , Anjali Gopal , Ghazal Haddad , Elodie Hatchi , Mohamed Helmy , Yves Jacob , Yoseph Kassa , Serena Landini , Roujia Li , Natascha van Lieshout , Andrew MacWilliams , Dylan Markey , Joseph N Paulson , Sudharshan Rangarajan , John Rasla , Ashyad Rayhan , Thomas Rolland , Adriana San-Miguel , Yun Shen , Dayag Sheykhkarimli , Gloria M Sheynkman , Eyal Simonovsky , Murat TaÅan , Alexander Tejeda , Vincent Tropepe , Jean-Claude Twizere , Yang Wang , Robert J Weatheritt , Jochen Weile , Yu Xia , Xinping Yang , Esti Yeger-Lotem , Quan Zhong , Patrick Aloy , Gary D Bader , Javier De Las Rivas , Suzanne Gaudet , Tong Hao , Janusz Rak , Jan Tavernier , David E Hill , Marc Vidal , Frederick P Roth , Michael A Calderwood |
2020-04-01 | - |
| 24223998 |
Lineage-specific expression of bestrophin-2 and bestrophin-4 in human intestinal epithelial cells. PLoS ONE Go Ito , Ryuichi Okamoto , Tatsuro Murano , Hiromichi Shimizu , Satoru Fujii , Toru Nakata , Tomohiro Mizutani , Shiro Yui , Junko Akiyama-Morio , Yasuhiro Nemoto , Eriko Okada , Akihiro Araki , Kazuo Ohtsuka , Kiichiro Tsuchiya , Tetsuya Nakamura , Mamoru Watanabe |
2013-01-01 |
BEST4,
BEST2
|
| 22360420 |
J. Proteome Res. Daniel Martins-de-Souza , Paul C Guest , David M Mann , Sigrun Roeber , Hassan Rahmoune , Corinna Bauder , Hans Kretzschmar , Benedikt Volk , Atik Baborie , Sabine Bahn |
2012-04-06 |
SLC25A13,
SIRPB1,
TUBB4B,
PRDX4,
TCFL5,
STIP1,
IMMT,
ERLIN2,
PRRT2,
STX1B,
HSPA12B,
NAXE,
GOT1L1,
VCAN,
CSRP1,
AP2A1,
AP2A2,
AP1B1,
AP2B1,
DDX10,
DECR1,
DNM2,
EEF1A1,
EIF4A2,
ENO2,
TUBB,
EVPL,
MYH15,
AKR1B1,
NCDN,
NEGR1,
TANC2,
PHGDH,
INTS6,
GFAP,
AMPH,
GLS,
GLUD1,
GLUD2,
GNAI1,
GPI,
GSTM3,
PSAT1,
HIP1,
HPRT1,
HSPA1A,
HSPB1,
HSP90AA1,
AQP4,
MAST4,
ARF5,
LDHA,
MDH1,
NDUFS1,
SEPT2,
ATP6V1H,
PGD,
BEST2,
PPP3CA,
PPP3CC,
PRKACA,
CAND1,
TDRD1,
PRPH,
CADM3,
RAN,
SDHA,
NOC3L,
SH3GL1,
SLC3A2,
SPTB,
STX1A,
STXBP1,
SYT1,
TCP1,
PRDX2,
TUBA4A,
TUBB2A,
HSP90AA5P,
VCP,
EZR,
CA1,
CALB2,
TUBA4B,
TUBB1,
CAMK2A,
CLTCL1,
SYN3,
HIST1H2BL,
HIST1H2BM,
CNTNAP1,
GBF1,
CBR1,
CBR3,
IGSF8,
SCRN1,
HNRNPDL
|
| 21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
| 20407206 |
Bestrophin-2 mediates bicarbonate transport by goblet cells in mouse colon. J Clin Invest Kuai Yu , Rafael Lujan , Alan Marmorstein , Sherif Gabriel , H Criss Hartzell |
2010-05-01 | - |
| 20157619 |
Mol Vis Youwen Zhang , Rajkumar V Patil , Alan D Marmorstein |
2010-02-10 | - |
| 19237432 |
Bestrophin expression and function in the human pancreatic duct cell line, CFPAC-1. J Physiol Laura L Marsey , John P Winpenny |
2009-05-15 | - |
| 19398034 |
Functional roles of bestrophins in ocular epithelia. Prog Retin Eye Res Alan D Marmorstein , Harold E Cross , Neal S Peachey |
2009-05-01 |
BEST2,
BEST1
|
| 16912113 |
Bestrophin-2 is a candidate calcium-activated chloride channel involved in olfactory transduction. Proc. Natl. Acad. Sci. U.S.A. Simone Pifferi , Giovanni Pascarella , Anna Boccaccio , Andrea Mazzatenta , Stefano Gustincich , Anna Menini , Silvia Zucchelli |
2006-08-22 |
Best2,
BEST2
|
| 14702039 |
Complete sequencing and characterization of 21,243 full-length human cDNAs. Nat. Genet. Toshio Ota , Yutaka Suzuki , Tetsuo Nishikawa , Tetsuji Otsuki , Tomoyasu Sugiyama , Ryotaro Irie , Ai Wakamatsu , Koji Hayashi , Hiroyuki Sato , Keiichi Nagai , Kouichi Kimura , Hiroshi Makita , Mitsuo Sekine , Masaya Obayashi , Tatsunari Nishi , Toshikazu Shibahara , Toshihiro Tanaka , Shizuko Ishii , Jun-ichi Yamamoto , Kaoru Saito , Yuri Kawai , Yuko Isono , Yoshitaka Nakamura , Kenji Nagahari , Katsuhiko Murakami , Tomohiro Yasuda , Takao Iwayanagi , Masako Wagatsuma , Akiko Shiratori , Hiroaki Sudo , Takehiko Hosoiri , Yoshiko Kaku , Hiroyo Kodaira , Hiroshi Kondo , Masanori Sugawara , Makiko Takahashi , Katsuhiro Kanda , Takahide Yokoi , Takako Furuya , Emiko Kikkawa , Yuhi Omura , Kumi Abe , Kumiko Kamihara , Naoko Katsuta , Kazuomi Sato , Machiko Tanikawa , Makoto Yamazaki , Ken Ninomiya , Tadashi Ishibashi , Hiromichi Yamashita , Katsuji Murakawa , Kiyoshi Fujimori , Hiroyuki Tanai , Manabu Kimata , Motoji Watanabe , Susumu Hiraoka , Yoshiyuki Chiba , Shinichi Ishida , Yukio Ono , Sumiyo Takiguchi , Susumu Watanabe , Makoto Yosida , Tomoko Hotuta , Junko Kusano , Keiichi Kanehori , Asako Takahashi-Fujii , Hiroto Hara , Tomo-o Tanase , Yoshiko Nomura , Sakae Togiya , Fukuyo Komai , Reiko Hara , Kazuha Takeuchi , Miho Arita , Nobuyuki Imose , Kaoru Musashino , Hisatsugu Yuuki , Atsushi Oshima , Naokazu Sasaki , Satoshi Aotsuka , Yoko Yoshikawa , Hiroshi Matsunawa , Tatsuo Ichihara , Namiko Shiohata , Sanae Sano , Shogo Moriya , Hiroko Momiyama , Noriko Satoh , Sachiko Takami , Yuko Terashima , Osamu Suzuki , Satoshi Nakagawa , Akihiro Senoh , Hiroshi Mizoguchi , Yoshihiro Goto , Fumio Shimizu , Hirokazu Wakebe , Haretsugu Hishigaki , Takeshi Watanabe , Akio Sugiyama , Makoto Takemoto , Bunsei Kawakami , Masaaki Yamazaki , Koji Watanabe , Ayako Kumagai , Shoko Itakura , Yasuhito Fukuzumi , Yoshifumi Fujimori , Megumi Komiyama , Hiroyuki Tashiro , Akira Tanigami , Tsutomu Fujiwara , Toshihide Ono , Katsue Yamada , Yuka Fujii , Kouichi Ozaki , Maasa Hirao , Yoshihiro Ohmori , Ayako Kawabata , Takeshi Hikiji , Naoko Kobatake , Hiromi Inagaki , Yasuko Ikema , Sachiko Okamoto , Rie Okitani , Takuma Kawakami , Saori Noguchi , Tomoko Itoh , Keiko Shigeta , Tadashi Senba , Kyoka Matsumura , Yoshie Nakajima , Takae Mizuno , Misato Morinaga , Masahide Sasaki , Takushi Togashi , Masaaki Oyama , Hiroko Hata , Manabu Watanabe , Takami Komatsu , Junko Mizushima-Sugano , Tadashi Satoh , Yuko Shirai , Yukiko Takahashi , Kiyomi Nakagawa , Koji Okumura , Takahiro Nagase , Nobuo Nomura , Hisashi Kikuchi , Yasuhiko Masuho , Riu Yamashita , Kenta Nakai , Tetsushi Yada , Yusuke Nakamura , Osamu Ohara , Takao Isogai , Sumio Sugano |
2004-01-01 |
Slc9a8,
Nefm,
Hfe2,
AKT3,
ZBTB11-AS1,
LOC100034248,
PDZK1P1,
DDTL,
LOC100049716,
ACOT8,
GNPDA1,
ZBTB33,
GTF2IP4,
POM121C,
ZSCAN30,
SRA1,
SNORD123,
UCKL1-AS1,
ZGLP1,
LOC100125918,
LINC00322,
LOC100127940,
HECW1-IT1,
LOC100127955,
LOC100127972,
LOC100127974,
FAM229A,
LOC100128076,
STAU2-AS1,
LOC100128164,
TMPO-AS1,
LOC100128219,
LOC100128239,
LOC100128253,
TNK2-AS1,
DNM1P35,
LOC100128288,
DLG5-AS1,
LOC100128310,
TRAPPC3L,
FAM83H-AS1,
LOC100128361,
LOC100128364,
FAM225B,
LOC100128386,
LOC100128398,
ASTN2-AS1,
C1orf132,
MYHAS,
LOC100128651,
LINC00476,
SRRM2-AS1,
GPR158-AS1,
LINC01165,
VPS9D1-AS1,
FAM66B,
GATA6-AS1,
LINC01310,
LOC100128979,
LOC100128988,
LOC100129034,
SEMA3F-AS1,
UNQ6494,
LOC100129115,
KHDC1L,
LOC100129175,
MATN1-AS1,
SLC39A12-AS1,
LOC100129297,
LOC100129312,
LINC00484,
LOC100129397,
LOC100129406,
DDC-AS1,
LOC100129434,
LOC100129447,
LOC100129455,
LYRM4-AS1,
ZNF37BP,
LOC100129516,
LOC100129518,
LOC100129540,
LOC100129572,
FAM47E,
LOC100129620,
LOC100129648,
C9orf173-AS1,
LOC100129775,
SLC25A21-AS1,
PCOLCE-AS1,
SCOC-AS1,
LOC100129884,
LOC100129894,
LOC100129917,
LOC100129935,
LOC100130078,
LOC100130111,
MAPT-IT1,
MIR124-2HG
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员