| Type | Description |
|---|---|
| Definition | ERCC excision repair 6 like, spindle assembly checkpoint helicase |
| Date | Results | Publications |
|---|---|---|
| 2021-02-02 13:29:00 | The ZATT-TOP2A-PICH Axis Drives Extensive Reversal to Promote Genome Stability. | 33296677 |
| 2020-07-11 12:33:00 | the present study provides preliminary evidence of the promoting effect of ERCC6L on the cell viability of RCC in vitro and in vivo. Further studies of the mechanisms underlying the regulation of ERCC6L may provide novel therapeutic targets in RCC. | 30459398 |
| 2020-07-11 11:52:00 | The study shows the dependency of triple-negative breast cancer cells on PICH for faithful chromosome segregation. | 31160555 |
| 2018-11-10 11:21:00 | These findings suggested that ERCC6L, which is highly expressed in breast cancer, acts as an oncogene, is involved in breast cancer development and may serve as a novel molecular target for the treatment of breast cancer. | 30066865 |
| 2018-04-07 11:29:00 | ERCC6L may stimulates cancer cell proliferation by promoting cell cycle through a way of RAB31-MAPK-CDK2, and it could be a potential biomarker for cancer prognosis and target for cancer treatment. | 28178669 |
| Type | IDs |
|---|---|
| Synonymous | PICH, RAD26L |
| Gene |
UniProtKB-ID:
ERC6L_HUMAN
UniprotKB:
Q2NKX8
UniParc:
UPI000021233E
EMBL:
EU069463,
BC111486,
AK074719,
BC008808,
AK000112,
AY121802
Ensembl:
ENSG00000186871
KO:
hsa:54821
|
| Nucleutide sequences |
EMBL-CDS:
ABU25227.1,
AAI11487.1,
BAA90952.1,
AAH08808.2,
BAC11160.1,
AAM82750.1
Ensembl_TRS:
ENST00000334463
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000334675
RefSeq:
NP_001009954.1,
NP_060139.2
|
| Others |
UniRef100:
UniRef100_Q2NKX8
UniRef90:
UniRef90_Q2NKX8
UniRef50:
UniRef50_Q2NKX8
UniGene:
Hs.47558
CCDS:
CCDS35329.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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