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54820 NDE1

54820

NDE1

nudE neurodevelopment protein 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition nudE neurodevelopment protein 1

研究结论

Date Results Publications
2021-02-20 13:29:00 CENP-F stabilizes kinetochore-microtubule attachments and limits dynein stripping of corona cargoes. 32207772
2020-11-21 13:18:00 [Microlissencephaly due to pathogenic variants of NDE1: from pathology to normal brain development].", trans "Variations pathogenes de NDE1 et microlissencephalie - De la pathologie au developpement cerebral normal. 33026328
2019-09-21 12:34:00 These studies identify the LIS1/NDE1 complex as an important FGF signaling regulator and provide insights into the bidirectional regulation of cell signaling and transport machinery for endocytosis. 29562183
2019-05-18 10:54:00 Nde1 makes unique contributions to human neurodevelopment through its regulation of both dynein and proteasome function. 30024347
2018-11-10 10:31:00 Our results show how evolutionary changes in cis as well as trans acting signals have played a fundamental role in determining NDE1 species specific splicing isoforms supporting the notion that alternative splicing plays a central role in human genome evolution, and possibly human cognitive predominance. 28266585

名称对应

Type IDs
Synonymous HOM-TES-87, LIS4, MHAC, NDE, NUDE, NUDE1
Gene
UniProtKB-ID: NDE1_HUMAN, X5DR54_HUMAN, X5DP35_HUMAN
UniprotKB: Q9NXR1, X5DR54, X5DP35
UniParc: UPI00003E8034, UPI0000073ECF, UPI0004437625
EMBL: KJ534887, KJ534991, BC033900, AK000108, BC001421, AC026401, AF001548, CH471226, GQ891334
Ensembl: ENSG00000072864, ENSG00000275911
KO: hsa:54820
Nucleutide sequences
EMBL-CDS: BAA90949.1, AAH01421.1, AAH33900.1, EAW53932.1, AHW56527.1, ADO22196.1, AHW56631.1
Gene_ORFName: hCG_38895
Ensembl_TRS: ENST00000396354, ENST00000396355, ENST00000631844, ENST00000631923
Protein sequencees
Ensembl_PRO: ENSP00000488199, ENSP00000379642, ENSP00000488050, ENSP00000379643
RefSeq: NP_060138.1, XP_016878838.1, XP_016878840.1, XP_011520855.1, XP_016878844.1, XP_006720963.1, XP_016878843.1, XP_016878845.1, NP_001137451.1, XP_006720960.1, XP_016878839.1, XP_005255453.1, XP_016878842.1, XP_016878841.1, XP_016878846.1
Others
UniRef100: UniRef100_X5DP35, UniRef100_Q9NXR1
UniRef90: UniRef90_Q9NXR1, UniRef90_A0A2I3MRN6
UniRef50: UniRef50_Q9NXR1, UniRef50_Q9ERR1-2
UniGene: Hs.655378
CCDS: CCDS10564.1

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