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54790 TET2

54790

TET2

tet methylcytosine dioxygenase 2

protein-coding

Homo sapiens

基因描述

Type Description
Definition tet methylcytosine dioxygenase 2

研究结论

Date Results Publications
2021-03-20 13:31:00 Germline TET2 loss of function causes childhood immunodeficiency and lymphoma. 32518946
2021-02-06 13:58:00 TET2 is involved in DNA hydroxymethylation, cell proliferation and inflammatory response in keratinocytes. 32319620
2021-01-23 12:56:00 TET2 promotor methylation and TET2 protein expression in pediatric posterior fossa ependymoma. 31777116
2020-12-26 13:15:00 BPA modulates the WDR5/TET2 complex to regulate ERbeta expression in eutopic endometrium and drives the development of endometriosis. 33022573
2020-12-26 13:13:00 Decreased vitamin C uptake mediated by SLC2A3 promotes leukaemia progression and impedes TET2 restoration. 32203209

名称对应

Type IDs
Synonymous KIAA1546, MDS
Gene
UniProtKB-ID: TET2_HUMAN, A0A158SIU0_HUMAN, A0A024RDF7_HUMAN
UniprotKB: Q6N021, A0A158SIU0, A0A024RDF7
UniParc: UPI00001D75E4, UPI0001A51BB7, UPI000020B29A
EMBL: FM992369, AK000039, AC026029, BC110510, AC004069, AK027819, CH471057, BX640738, AB046766, BC110509, AB075496
Ensembl: ENSG00000168769
KO: hsa:54790
Nucleutide sequences
EMBL-CDS: AAI10510.1, BAB55391.1, CAE45851.1, AAI10511.2, BAA90898.1, BAB13372.1, BAE45750.1, CAX30492.1, EAX06178.1, EAX06177.1
Gene_ORFName: Nbla00191, hCG_1778365
Ensembl_TRS: ENST00000380013, ENST00000265149, ENST00000540549, ENST00000305737
Protein sequencees
Ensembl_PRO: ENSP00000369351, ENSP00000306705, ENSP00000265149, ENSP00000442788
RefSeq: XP_024309871.1, XP_005263139.1, XP_024309870.1, XP_006714305.1, NP_001120680.1, NP_060098.3, XP_016863808.1
Others
UniRef100: UniRef100_A0A024RDF7, UniRef100_Q6N021
UniRef90: UniRef90_Q6N021, UniRef90_Q6N021-3
UniRef50: UniRef50_Q6N021, UniRef50_Q6N021-3
UniGene: Hs.367639, Hs.706276
CCDS: CCDS3666.1, CCDS47120.1

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