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54751 FBLIM1

54751

FBLIM1

filamin binding LIM protein 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition filamin binding LIM protein 1

研究结论

Date Results Publications
2020-07-18 11:22:00 Genetic analyses of FBLIM1 did not provide evidence that this gene is relevant in our patient group. Our study indicates the need to elucidate SAPHO's and CRMO/CNO's pathogenesis. 32397996
2019-12-28 10:04:00 Findings indicate that tightly regulated expression of migfilin is essential for neuronal development and that FBLIM1 disruption may be related to the phenotypes associated with ASD and related neurodevelopmental disorders. 29114925
2019-05-18 10:50:00 Results showed FBLIM1 overexpression in oral squamous cell carcinoma (OSCC) in vitro and in vivo and that FBLIM1 positivity in OSCC was correlated with tumoral growth and vascular invasion. FBLIM1 silencing was characterized by decreased cellular growth, invasiveness, and migratory activities and induced EGFR down-regulation. 30129678
2019-03-30 12:48:00 Authors conclude that circFBLIM1 may function as a competing endogenous RNA (ceRNA) to regulate FBLIM1 expression through sponging miR-346 to exert regulatory functions in HCC. 30053867
2019-03-02 11:04:00 Migfilin promotes migration and invasion in glioma by driving EGFR and MMP-2 signalings 29203120

名称对应

Type IDs
Synonymous CAL, FBLP-1, FBLP1
Gene
UniProtKB-ID: FBLI1_HUMAN
UniprotKB: Q8WUP2
UniParc: UPI0000520D52, UPI000013F27B, UPI000013E169
EMBL: AK055259, AL133035, AK027444, AY180161, BC019895, AL450998, AF459643
Ensembl: ENSG00000162458
KO: hsa:54751
Nucleutide sequences
EMBL-CDS: CAB61365.1, BAG51492.1, AAO15549.1, AAH19895.1, BAB55115.1, AAO49012.1
Ensembl_TRS: ENST00000441801, ENST00000375771, ENST00000332305, ENST00000375766
Protein sequencees
Ensembl_PRO: ENSP00000364926, ENSP00000364921, ENSP00000364920, ENSP00000416387
RefSeq: XP_016857012.1, XP_006710767.1, XP_011539920.1, XP_005245959.1, XP_016857010.1, XP_016857013.1, XP_016857009.1, XP_016857008.1, XP_011539919.1, NP_001019386.1, XP_016857014.1, NP_001337080.1, XP_005245957.1, XP_016857015.1, NP_060026.2, XP_024303519.1, NP_001019387.1, XP_005245958.1, XP_005245960.1, XP_006710768.1, XP_011539918.1
Others
UniRef100: UniRef100_Q8WUP2
UniRef90: UniRef90_Q8WUP2
UniRef50: UniRef50_Q8WUP2
UniGene: Hs.530101
CCDS: CCDS44064.1, CCDS30609.1, CCDS163.1

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