| Type | Description |
|---|---|
| Definition | M-phase phosphoprotein 8 |
| Date | Results | Publications |
|---|---|---|
| 2018-08-11 10:04:00 | The study demonstrated that MPP8 was associated with non-small cell lung cancer cell proliferation through regulation of HOXA5. | 29412790 |
| 2017-01-14 11:56:00 | The haploid screen identified HUSH, an epigenetic heterochromatin repressor complex composed of three subunits, TASOR, MPP8 and Periphilin. (Review) | 26853531 |
| 2016-03-12 10:52:00 | findings demonstrate MPP8 and SIRT1 reciprocally regulate each other's function at multiple molecular layers through physical interaction; disruption of MPP8-SIRT1 interaction de-represses E cadherin expression and reduces cell motility and invasiveness suggesting this interplay plays critical role in MPP8- and SIRT1-mediated epithelial-mesenchymal transition | 25870236 |
| 2015-07-25 10:58:00 | this study identified the HUSH (human silencing hub) complex, comprising three poorly characterized proteins, TASOR, MPP8, and periphilin; this complex is absent from Drosophila but is conserved from fish to humans. | 26022416 |
| 2015-05-16 11:43:00 | Knockdown analysis of MPP8 in HeLa cells resulted in derepression of a set of genes that are normally expressed in spermatogonia, spermatids and mature sperm, thereby indicating a role for this molecule in silencing testis-related genes in somatic cells. | 25660450 |
| Type | IDs |
|---|---|
| Synonymous | HSMPP8, TWA3, mpp8 |
| Gene |
UniProtKB-ID:
MPP8_HUMAN
UniprotKB:
Q99549
UniParc:
UPI0000051C18,
UPI000013F34D
EMBL:
BC003542,
AL354808,
AK056785,
AL832864,
AL359457,
AK300258,
X98259,
CH471075,
BC046214
Ensembl:
ENSG00000196199
KO:
hsa:54737
|
| Nucleutide sequences |
EMBL-CDS:
AAH03542.2,
BAH13245.1,
BAB71284.1,
CAA66912.1,
AAH46214.1,
EAX08230.1,
CAI46172.1,
EAX08228.1
Ensembl_TRS:
ENST00000361479
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000355388
RefSeq:
NP_059990.2,
XP_011533426.1
|
| Others |
UniRef100:
UniRef100_Q99549
UniRef90:
UniRef90_Q99549
UniRef50:
UniRef50_Q99549
UniGene:
Hs.269654
CCDS:
CCDS9287.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员