| Type | Description |
|---|---|
| Definition | mediator complex subunit 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-11-21 13:23:00 | Molecular determinants of MED1 interaction with the DNA bound VDR-RXR heterodimer. | 32990725 |
| 2020-10-10 13:00:00 | Genetic variants of the peroxisome proliferator-activated receptor (PPAR) signaling pathway genes and risk of pancreatic cancer. | 32367578 |
| 2020-07-18 12:04:00 | Here, we report that, in human cancer cells, BRD4S forms nuclear puncta that possess liquid-like properties and that colocalize with BRD4L, MED1 and sites of histone H3 lysine 27 acetylation. BRD4 puncta are correlated with BRD4S but not BRD4L expression levels. | 32203489 |
| 2020-02-15 12:37:00 | It has been demonstrated that induction of double-strand DNA breaks results in the assembly of functional promoters that include a complete RNA polymerase II preinitiation complex, MED1 and CDK9. | 31570834 |
| 2019-12-14 10:05:00 | MED1 is an estrogen receptor coactivator that is a tissue-specific therapeutic target in breast cancer [review] | 31090264 |
| Type | IDs |
|---|---|
| Synonymous | CRSP1, CRSP200, DRIP205, DRIP230, PBP, PPARBP, PPARGBP, RB18A, TRAP220, TRIP2 |
| Gene |
UniProtKB-ID:
MED1_HUMAN
UniprotKB:
Q15648
UniParc:
UPI00002132C2,
UPI0000167F57
EMBL:
CH471152,
BC006517,
AF283812,
BC060758,
BC131783,
L40366,
Y13467,
AF055994
Ensembl:
ENSG00000125686
KO:
hsa:5469
|
| Nucleutide sequences |
EMBL-CDS:
AAI31784.1,
AAC39854.1,
AAH06517.1,
AAH60758.1,
AAF98352.1,
EAW60575.1,
CAA73867.1,
AAC41736.1
Ensembl_TRS:
ENST00000300651,
ENST00000394287
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000300651,
ENSP00000377828
RefSeq:
XP_006722020.1,
NP_004765.2,
XP_005257522.1,
XP_016880268.1
|
| Others |
UniRef100:
UniRef100_Q15648
UniRef90:
UniRef90_Q15648
UniRef50:
UniRef50_Q15648
UniGene:
Hs.643754
CCDS:
CCDS11336.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员