| Type | Description |
|---|---|
| Definition | prolyl 4-hydroxylase, transmembrane |
| Date | Results | Publications |
|---|---|---|
| 2017-12-30 10:03:00 | The results suggest that SESN2 increases degradation of HIF-1A via AMPK-PHD regulation that contributes to inhibition of in vitro and in vivo tumorigenesis. | 27840318 |
| 2015-01-17 12:45:00 | This review will expand our knowledge of biology of HIFs, PHDs, PHD inhibitors, and bone regeneration, and it may also aid the design of novel therapies for accelerating bone repair and regeneration or inhibiting bone tumours. [review] | 24895555 |
| 2013-08-31 10:42:00 | Results suggest that increased expression of prolyl hydroxylase (PH) might play an role in the physiology of uterine leiomyoma during the menstrual cycle. | 23241241 |
| 2010-01-21 00:00:00 | the longest and shortest isoenzymes have major transcripts encoding inactive polypeptides, which suggest novel regulation by alternative splicing. | 12788921 |
| 2010-01-21 00:00:00 | Data suggest that PH-4 is a novel hypoxia-inducible factor-prolyl hydroxylase that may be involved in the degradation of hypoxia-inducible transcription factors under normoxia. | 12163023 |
| Type | IDs |
|---|---|
| Synonymous | EGLN4, HIFPH4, P4H-TM, PH-4, PH4, PHD4 |
| Gene |
UniProtKB-ID:
P4HTM_HUMAN
UniprotKB:
Q9NXG6
UniParc:
UPI0000185F54,
UPI0000185F98,
UPI0000209C68
EMBL:
AY198406,
BC047566,
BC000580,
BC060321,
AL713728,
BC011710,
AK000269
Ensembl:
ENSG00000178467
KO:
hsa:54681
|
| Nucleutide sequences |
EMBL-CDS:
CAD28518.2,
BAA91045.1,
AAH00580.1,
AAO43431.1,
AAH60321.1,
AAH47566.1,
AAH11710.3
Ensembl_TRS:
ENST00000343546,
ENST00000383729
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000341422,
ENSP00000373235
RefSeq:
NP_808808.1,
NP_808807.2
|
| Others |
UniRef100:
UniRef100_Q9NXG6
UniRef90:
UniRef90_Q9NXG6
UniRef50:
UniRef50_Q9NXG6
UniGene:
Hs.654944
CCDS:
CCDS43089.1,
CCDS2781.2
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员