| Type | Description |
|---|---|
| Definition | calcium channel, voltage-dependent, alpha 1F subunit |
| Date | Results | Publications |
|---|---|---|
| 2021-02-20 13:30:00 | A dual role for Cav1.4 Ca(2+) channels in the molecular and structural organization of the rod photoreceptor synapse. | 32940604 |
| 2020-12-05 13:03:00 | Synaptic ribbons foster active zone stability and illumination-dependent active zone enrichment of RIM2 and Cav1.4 in photoreceptor synapses. | 32249787 |
| 2019-08-24 10:07:00 | The novel finding of cone-to-rod-bipolar cell contacts in this mouse model of a retinal channelopathy may challenge current views of the role of Cacna1f in photopic vision, it also suggests a potential new target for restorative therapy. | 29179637 |
| 2019-04-20 10:18:00 | No cone ERGs could be detected from residual cones, in which S-opsins abnormally migrated to inner segments of the photoreceptors. The mutations of the Cacna1f gene in nob9 mice involved both a single nucleotide G to A transition and a 10-nucleotide insertion, the latter resulting in a frame-shift mutation in exon 14. | 30445045 |
| 2017-07-29 11:24:00 | Results show that genetic deletion of the synaptic Cav1.4 L-type voltage-gated calcium channels impairs calpain activation and leads to a short-term preservation of photoreceptors in the rd1 mouse. | 27270916 |
| Type | IDs |
|---|---|
| Synonymous | A930034B14, Cav1.4, Sfc17, nerg1, nob2 |
| Gene |
UniProtKB-ID:
Q7TNI3_MOUSE
UniprotKB:
Q7TNI3
UniParc:
UPI00001B673E
EMBL:
AJ579852,
AL672231
Ensembl:
ENSMUSG00000031142
KO:
mmu:54652
|
| Nucleutide sequences |
EMBL-CDS:
CAE30292.1
Ensembl_TRS:
ENSMUST00000115726
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000111391
RefSeq:
NP_062528.2,
XP_030107268.1
|
| Others |
UniRef100:
UniRef100_Q7TNI3
UniRef90:
UniRef90_Q9JIS7
UniRef50:
UniRef50_Q9JIS7
UniGene:
Mm.289647
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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