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5464 PPA1

5464

PPA1

pyrophosphatase (inorganic) 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition pyrophosphatase (inorganic) 1

研究结论

Date Results Publications
2020-09-05 13:55:00 PP1 and PP2A Use Opposite Phospho-dependencies to Control Distinct Processes at the Kinetochore. 31433993
2020-06-20 11:16:00 CDK1-counteracting phosphatases PP1 and PP2A-B55, together with Aurora and Polo kinases, contribute to the temporal regulation and order of events in the different stages of mitotic exit from anaphase to cytokinesis. (Review) 31494926
2019-11-23 11:17:00 PP1-NIPP1 expression resulted in the build up of RNA-DNA hybrids (R-loops), enhanced chromatin compaction and a diminished repair of DNA double-strand breaks. 29898919
2019-10-19 11:38:00 Study identified phosphorylation of RV[S/T]F motifs in known and previously unidentified PP1 regulatory proteins as a cell cycle-dependent event and shows that Aurora B was the primary kinase responsible for this phosphorylation event during mitosis. 29764992
2018-12-22 10:12:00 The p37 controls cortical NuMA levels via the phosphatase PP1 and its regulatory subunit Repo-Man, but it acts independently of Galphai, the kinase Aurora A, and the phosphatase PP2A. 29222185

名称对应

Type IDs
Synonymous HEL-S-66p, IOPPP, PP, PP1, SID6-8061
Gene
UniProtKB-ID: IPYR_HUMAN, V9HWB5_HUMAN
UniprotKB: Q15181, V9HWB5
UniParc: UPI000012D838
EMBL: BC105036, AF154065, AL731540, BC001022, BC107882, AF108211, BC061581, CH471083, BC105034, Z48605, AB026723, EU794626, AF217186, AF119665, AF092439
Ensembl: ENSG00000180817
KO: hsa:5464
Nucleutide sequences
EMBL-CDS: AAD24964.1, AAD34643.1, AAH61581.2, AAI05037.1, AAG36780.1, AAI07883.1, CAA88494.1, AAF17222.1, AAH01022.3, AAP97214.1, BAA84702.1, AAI05035.1, EAW54383.1, EAW54386.1, ACJ13680.1
Gene_ORFName: hCG_2024809
Ensembl_TRS: ENST00000373232
Protein sequencees
Ensembl_PRO: ENSP00000362329
RefSeq: NP_066952.1
Others
UniRef100: UniRef100_Q15181
UniRef90: UniRef90_Q15181
UniRef50: UniRef50_Q15181
UniGene: Hs.437403
CCDS: CCDS7299.1

全选

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