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54631 Nphs1

54631

Nphs1

nephrosis 1, nephrin

protein-coding

Mus musculus

基因描述

Type Description
Definition nephrosis 1, nephrin

研究结论

Date Results Publications
2019-05-18 12:09:00 IL-7 stimulation inhibited nephrin activation and caused actin cytoskeleton disorganization, indicating that IL-7 stimulation induces podocyte injury. 30454893
2019-04-13 10:07:00 WNT/beta-catenin signaling is crucial for myoblast fusion through the regulation of the Nphs1 gene. 30389854
2018-12-22 12:01:00 Nephrin is necessary for podocyte recovery following injury in an adult mature glomerulus 29924795
2018-03-24 10:39:00 Here, we found the dynamic changes of Notch1 were coincided with autophagy: they both increased during kidney development and podocyte differentiation...to better understand the relationship between Notch signalling and autophagy in podocyte differentiation, rapamycin was added to enhance autophagy levels in DAPT-treated cells, and as a result, nephrin was recovered and DAPT-induced injury was ameliorated 28158917
2017-08-12 10:25:00 WHSC1L1-L acts as a histone methyltransferase in podocytes and regulates nephrin gene expression, which may in turn contribute to the integrity of the slit diaphragm of the glomerular filtration barrier. 28228401

名称对应

Type IDs
Synonymous NephrinB, nephrin
Gene
UniProtKB-ID: NPHN_MOUSE
UniprotKB: Q9QZS7
UniParc: UPI00001F4D00, UPI0000563DF9
EMBL: AF172256, AF168466, AF172251, AF172253, AF172247, AF172254, AY183460, AF172250, AB513652, AF172248, AC167970, AF172252, AF190638, AF191090, AF172249
Ensembl: ENSMUSG00000006649
KO: mmu:54631
Nucleutide sequences
EMBL-CDS: AAK38483.1, AAF91087.1, AAO22850.1, AAG17142.1, AAF03368.1, BAI63574.1, AAF91085.1
Ensembl_TRS: ENSMUST00000126297, ENSMUST00000006825
Protein sequencees
Ensembl_PRO: ENSMUSP00000116500, ENSMUSP00000006825
RefSeq: XP_011248949.1, NP_062332.2, XP_036009153.1, XP_036009152.1
Others
UniRef100: UniRef100_Q9QZS7
UniRef90: UniRef90_Q9QZS7
UniRef50: UniRef50_O60500
UniGene: Mm.437830
CCDS: CCDS39884.1

全选

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