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54623 PAF1

54623

PAF1

PAF1 homolog, Paf1/RNA polymerase II complex component

protein-coding

Homo sapiens

基因描述

Type Description
Definition PAF1 homolog, Paf1/RNA polymerase II complex component

研究结论

Date Results Publications
2021-04-17 13:16:00 II-Associated Factor 1 Regulates Stem Cell Features of Pancreatic Independently of the PAF1 Complex, via Interactions With PHF5A and DDX3. 32781084
2021-04-03 13:29:00 Novel role of PAF1 in attenuating radiosensitivity in cervical cancer by inhibiting IER5 transcription. 32471508
2021-03-20 13:35:00 A CSB-PAF1C axis restores processive transcription elongation after DNA damage repair. 33637760
2019-07-06 12:51:00 These data highlight that human PAF1C is an important transcriptional regulator of expanded G4C2 within C9orf72 31110321
2019-01-19 10:07:00 Study reports 2.53 A atomic structures of both the human PAF1/CTR9 and yeast Paf1/Ctr9 heterodimers. Results clearly reveal that the heterodimer of PAF1/CTR9 or Paf1/Ctr9 is the core component of evolutionarily conserved multifunctional polymerase-associated factor 1 complex (Paf1C) and is important for human PAF1C or yeast Paf1C assembly, yeast viability, and Paf1C-mediated histone modifications. 30228257

名称对应

Type IDs
Synonymous F23149_1, PD2
Gene
UniProtKB-ID: PAF1_HUMAN, A0A024R0H6_HUMAN
UniprotKB: Q8N7H5, A0A024R0H6
UniParc: UPI000006D489, UPI000170BA59, UPI000059D71D
EMBL: AK001985, BC013402, AK098423, CH471126, AC005239, BC000017, AJ401156
Ensembl: ENSG00000006712
KO: hsa:54623
Nucleutide sequences
EMBL-CDS: EAW56880.1, BAA92020.1, EAW56883.1, BAC05305.1, AAH13402.1, AAC25503.1, AAH00017.1, EAW56881.1, CAC20564.1, EAW56882.1
Gene_ORFName: hCG_43356
Ensembl_TRS: ENST00000595564, ENST00000221265
Protein sequencees
Ensembl_PRO: ENSP00000468874, ENSP00000221265
RefSeq: NP_001243755.1, NP_061961.2
Others
UniRef100: UniRef100_Q8N7H5
UniRef90: UniRef90_Q8N7H5
UniRef50: UniRef50_Q8N7H5
UniGene: Hs.466714
CCDS: CCDS59387.1, CCDS12533.1

全选

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研究热度

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