| Type | Description |
|---|---|
| Definition | DEAD-box helicase 56 |
| Date | Results | Publications |
|---|---|---|
| 2020-09-26 13:02:00 | DDX56 inhibits type I interferon by disrupting assembly of IRF3-IPO5 to inhibit IRF3 nucleus import. | 31340999 |
| 2019-10-12 12:43:00 | Study identified DDX56 as a novel oncogene on chromosome 7p and a prognostic biomarker of colorectal cancer (CRC). DDX56 can induce oncogenic splicing abnormalities of the G2-M cell cycle checkpoint gene WEE1 which contributes to the inhibition of proliferation and cell cycle progression. | 31390121 |
| 2017-06-24 10:57:00 | West Nile virus infection results in relocalization of DDX56 from nucleoli to virus assembly sites on the endoplasmic reticululm (ER), an observation that is consistent with a role for DDX56 in WNV virion assembly. | 27821284 |
| 2013-01-05 10:23:00 | The helicase activity of DDX56 is required for its role in assembly of infectious West Nile virus particles. | 22925334 |
| 2011-07-16 10:50:00 | Coimmunoprecipitation confirmed that capsid protein binds to human DDX56 in infected cells and that this interaction is required for assembly of infectious West Nile virus particles. | 21411523 |
| Type | IDs |
|---|---|
| Synonymous | DDX21, DDX26, NOH61 |
| Gene |
UniProtKB-ID:
DDX56_HUMAN
UniprotKB:
Q9NY93
UniParc:
UPI000198CDE1,
UPI0000037BB1
EMBL:
AF247666,
CR457213,
AJ131712,
CH471128,
BC001235,
CH236960,
AK022774,
AC004938,
AL136700,
AK315363
Ensembl:
ENSG00000136271
KO:
hsa:54606
|
| Nucleutide sequences |
EMBL-CDS:
AAH01235.1,
CAB66635.1,
CAB87992.1,
BAB14238.1,
EAW61094.1,
CAG33494.1,
EAL23752.1,
AAG36876.1
Ensembl_TRS:
ENST00000431640,
ENST00000258772
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000258772,
ENSP00000393488
RefSeq:
NP_001244118.1,
NP_061955.1
|
| Others |
UniRef100:
UniRef100_Q9NY93
UniRef90:
UniRef90_Q9NY93
UniRef50:
UniRef50_Q9NY93
UniGene:
Hs.654762
CCDS:
CCDS59053.1,
CCDS5492.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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