C330021F23Rik - RIKEN cDNA C330021F23 gene-BMKCloudï½ç¾è¿å®¢äº

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546049 C330021F23Rik

基因描述

Type	Description
Definition	RIKEN cDNA C330021F23 gene

研究结论

Date	Results	Publications
2020-08-12 13:08:00	The study results reveal a role for RPS23RG1 in maintaining synaptic integrity and function and provide a new mechanism for synaptic dysfunction in Alzheimer's disease (AD) pathogenesis.	30292394
2016-12-17 11:37:00	Our study demonstrates that RPS23RG1 may reduce the occurrence of key elements of AD pathology and enhance synaptic functions to counteract oAbeta-induced synaptic and cognitive deficits in AD	26733416
2011-05-10 11:21:00	We provide compelling evidence to show that RPS23R1 overexpression can reduce both beta-amyloid levels and tau phosphorylation, two major pathological hallmarks of Alzheimer's disease	19914182

名称对应

Type	IDs
Synonymous	2610027C06Rik, Rps23r1, Rps23rg1
Gene	UniProtKB-ID: Q8C7T0_MOUSE UniprotKB: Q8C7T0 UniParc: UPI00000E9993 EMBL: AC170806, AK049309, BC089480 Ensembl: ENSMUSG00000065952 KO: mmu:546049
Nucleutide sequences	EMBL-CDS: AAH89480.1, BAC33674.1 Ensembl_TRS: ENSMUST00000136592, ENSMUST00000086479
Protein sequencees	Ensembl_PRO: ENSMUSP00000136628, ENSMUSP00000123235 RefSeq: NP_001019899.1
Others	UniRef100: UniRef100_Q8C7T0 UniRef90: UniRef90_Q8C7T0 UniRef50: UniRef50_Q8C7T0 UniGene: Mm.358733, Mm.428003

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mRNA

Protein

UniprotKB

Description

Refseq

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Ensembl: {{protein.nucleotideEnsembl}}

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Ensembl: {{protein.proteinEnsembl}}

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Status: {{protein.status}}

Location

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Pubmed编号	文献信息	发表日期	相关基因
30292394	RPS23RG1 Is Required for Synaptic Integrity andÂ Rescues Alzheimer's Disease-Associated CognitiveÂ Deficits. Biol Psychiatry Dongdong Zhao , Jian Meng , Yingjun Zhao , Yuanhui Huo , Yan Liu , Naizhen Zheng , Muxian Zhang , Yue Gao , Zhicai Chen , Hao Sun , Xiangyu Wang , Chuya Jing , Tongmei Zhang , Xian Zhang , Hong Luo , Xin Wang , Jie Zhang , Fa-Rong Liu , Yanfang Li , Guojun Bu , Lei Wen , Timothy Y Huang , Huaxi Xu , Yun-Wu Zhang	2019-08-01	-
26733416	RPS23RG1 reduces AÎ² oligomer-induced synaptic and cognitive deficits. Sci Rep Li Yan , Yaomin Chen , Wubo Li , Xiumei Huang , Hedieh Badie , Fan Jian , Timothy Huang , Yingjun Zhao , Stanley N Cohen , Limin Li , Yun-Wu Zhang , Huanmin Luo , Shichun Tu , Huaxi Xu	2016-01-01	-
20650958	The Rps23rg gene family originated through retroposition of the ribosomal protein s23 mRNA and encodes proteins that decrease Alzheimer's beta-amyloid level and tau phosphorylation. Hum Mol Genet Xiumei Huang , Yaomin Chen , Wu-Bo Li , Stanley N Cohen , Francesca-Fang Liao , Limin Li , Huaxi Xu , Yun-Wu Zhang	2010-10-01	-
19914182	A functional mouse retroposed gene Rps23r1 reduces Alzheimer's beta-amyloid levels and tau phosphorylation. Neuron Yun-wu Zhang , Shijie Liu , Xue Zhang , Wu-Bo Li , Yaomin Chen , Xiumei Huang , Liangwu Sun , Wenjie Luo , William J Netzer , Richard Threadgill , Gordon Wiegand , Ruishan Wang , Stanley N Cohen , Paul Greengard , Francesca-Fang Liao , Limin Li , Huaxi Xu	2009-11-12	C330021F23Rik
18799693	Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome Res. Gwenn M Hansen , Diane C Markesich , Michael B Burnett , Qichao Zhu , Karen M Dionne , Lizabeth J Richter , Richard H Finnell , Arthur T Sands , Brian P Zambrowicz , Alejandro Abuin	2008-10-01	Gm11335, Gm17762, A930017K11Rik, BC028777, Gm13999, Gm11696, Gm12359, Gm10589, D030047H15Rik, Gm10856, Gm10685, Gm10062, Gm10433, Gm10648, Gm10840, Gm15441, Gm10684, Gm9900, Gm10822, Gm10687, Gm11744, Gm10747, Arih2os, B230344G16Rik, Fmr1os, Tmem51os1, Gm14488, Gm13033, Gm10789, Gm10615, Gm1976, Gm9967, Gm9917, Gm1974, Gm11496, Gm13580, Gm2085, Gm2183, Gm2245, Tbx3os1, Gm12980, Gm2329, Lncenc1, Gm2381, Snhg12, Gm2479, Gm12942, Gm2529, Gm2533, Rpl30-ps7, Rsf1os2, Gm2695, 2810416G20Rik, Rpl30-ps6, Gm2773, Gm2788, Dynlt1f, Gm9793, Gm2885, Gm2920, Gm15506, Gm11627, Gm10518, Gm13496, Gm3134, Gm12827, Gm3143, Gm10144, Ahnak2, Gm3196, Gm13242, Gm3325, Gm13247, Gm10863, Gm13157, 4930522L14Rik, Gm3552, Gm15226, Gm3604, Gm3643, BC005561, Gm3716, 2810410L24Rik, Gm10282, Gm3839, Nhsl2, 4732419C18Rik, Gm3906, Gm3973, Gm4013, Apol7d, Gm12057, Gm10489, Rex2, 1110002L01Rik, Gm4189, Gm4204, 4632428C04Rik, 9130023H24Rik
17967808	EUCOMM--the European conditional mouse mutagenesis program. Brief Funct Genomic Proteomic Roland H Friedel , Claudia Seisenberger , Cornelia Kaloff , Wolfgang Wurst	2007-09-01	Gm11696, Gm10589, Apela, Gm10822, Gm2085, Gm2312, Lncenc1, Gm2381, Gm2659, Gm2679, Dynlt1c, Gm3134, Gm3143, Gm3236, Gm3574, Gm3581, Gm3718, Gm3859, Gm3905, Gm3952, Gm3957, Gm3973, Gm12057, Rex2, Gm4218, Gm4225, Gm16476, Gm4407, Gm14410, Gm4420, Gm14005, 1300002E11Rik, Gm4532, Srcap, Gm17789, Gm10751, Gm14321, 0610009E02Rik, Gm12758, Gm11532, Phactr4, Rusc2, AK010878, Gm10778, 5830417I10Rik, Mir1902, Gm15270, Gm11767, Ino80dos, Bsdc1, Gm7645, Gm20590, Slc44a1, Gm15545, Gm17292, 2900009J06Rik, Kifc1, Gm13150, Gm19426, Gm19428, Gm19474, Gm14963, Gm19565, Gm19592, Gm12588, Snhg4, Gm19702, Gm19705, Platr22, Nuggc, Zfp534, Gm19860, Gm11725, Gm19876, Gm19889, Gm16201, Gm13056, Tnfsf13os, Gm19925, Gm19976, Gm20014, Gm16740, Gm20039, Gm20045, AU020206, Ccdc170, Trp53cor1, Gm20266, Gm20324, Zfp518b, Gm14401, AI480526, Pds5b, Ube3c, Gm21297, Akap9, Gm29724, Itfg2, Parp11
16141072	The transcriptional landscape of the mammalian genome. Science P Carninci , T Kasukawa , S Katayama , J Gough , M C Frith , N Maeda , R Oyama , T Ravasi , B Lenhard , C Wells , R Kodzius , K Shimokawa , V B Bajic , S E Brenner , S Batalov , A R R Forrest , M Zavolan , M J Davis , L G Wilming , V Aidinis , J E Allen , A Ambesi-Impiombato , R Apweiler , R N Aturaliya , T L Bailey , M Bansal , L Baxter , K W Beisel , T Bersano , H Bono , A M Chalk , K P Chiu , V Choudhary , A Christoffels , D R Clutterbuck , M L Crowe , E Dalla , B P Dalrymple , B de Bono , G Della Gatta , D di Bernardo , T Down , P Engstrom , M Fagiolini , G Faulkner , C F Fletcher , T Fukushima , M Furuno , S Futaki , M Gariboldi , P Georgii-Hemming , T R Gingeras , T Gojobori , R E Green , S Gustincich , M Harbers , Y Hayashi , T K Hensch , N Hirokawa , D Hill , L Huminiecki , M Iacono , K Ikeo , A Iwama , T Ishikawa , M Jakt , A Kanapin , M Katoh , Y Kawasawa , J Kelso , H Kitamura , H Kitano , G Kollias , S P T Krishnan , A Kruger , S K Kummerfeld , I V Kurochkin , L F Lareau , D Lazarevic , L Lipovich , J Liu , S Liuni , S McWilliam , M Madan Babu , M Madera , L Marchionni , H Matsuda , S Matsuzawa , H Miki , F Mignone , S Miyake , K Morris , S Mottagui-Tabar , N Mulder , N Nakano , H Nakauchi , P Ng , R Nilsson , S Nishiguchi , S Nishikawa , F Nori , O Ohara , Y Okazaki , V Orlando , K C Pang , W J Pavan , G Pavesi , G Pesole , N Petrovsky , S Piazza , J Reed , J F Reid , B Z Ring , M Ringwald , B Rost , Y Ruan , S L Salzberg , A Sandelin , C Schneider , C SchÃ¶nbach , K Sekiguchi , C A M Semple , S Seno , L Sessa , Y Sheng , Y Shibata , H Shimada , K Shimada , D Silva , B Sinclair , S Sperling , E Stupka , K Sugiura , R Sultana , Y Takenaka , K Taki , K Tammoja , S L Tan , S Tang , M S Taylor , J Tegner , S A Teichmann , H R Ueda , E van Nimwegen , R Verardo , C L Wei , K Yagi , H Yamanishi , E Zabarovsky , S Zhu , A Zimmer , W Hide , C Bult , S M Grimmond , R D Teasdale , E T Liu , V Brusic , J Quackenbush , C Wahlestedt , J S Mattick , D A Hume , C Kai , D Sasaki , Y Tomaru , S Fukuda , M Kanamori-Katayama , M Suzuki , J Aoki , T Arakawa , J Iida , K Imamura , M Itoh , T Kato , H Kawaji , N Kawagashira , T Kawashima , M Kojima , S Kondo , H Konno , K Nakano , N Ninomiya , T Nishio , M Okada , C Plessy , K Shibata , T Shiraki , S Suzuki , M Tagami , K Waki , A Watahiki , Y Okamura-Oho , H Suzuki , J Kawai , Y Hayashizaki , FANTOM Consortium , RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)	2005-09-02	-
16141073	Antisense transcription in the mammalian transcriptome. Science S Katayama , Y Tomaru , T Kasukawa , K Waki , M Nakanishi , M Nakamura , H Nishida , C C Yap , M Suzuki , J Kawai , H Suzuki , P Carninci , Y Hayashizaki , C Wells , M Frith , T Ravasi , K C Pang , J Hallinan , J Mattick , D A Hume , L Lipovich , S Batalov , P G EngstrÃ¶m , Y Mizuno , M A Faghihi , A Sandelin , A M Chalk , S Mottagui-Tabar , Z Liang , B Lenhard , C Wahlestedt , RIKEN Genome Exploration Research Group , Genome Science Group (Genome Network Project Core Group) , FANTOM Consortium	2005-09-02	Gm14018, Gm14964, F630206G17Rik, Oog3, Notumos, Ldlrap1, Mdn1, Pydc3, 9330171B17Rik, Mfap1b, Tmsb15b2, Gm12802, E430020m11rik, Gm11335, Gm15772, Gm17762, A930017K11Rik, LOC100036513, Gata5os, Umad1, Gm16982, Gm9887, Gm9872, LOC100036530, Gm9934, Gm9913, Gm11149, BC028777, Gm13999, LOC100036540, Gm9744, Gm9983, D630002J18Rik, Gm16525, Gm11696, Dnajc3, 9430060I03Rik, Gm12359, 4921516A02Rik, Fam129c, Gm10589, Rsph3b, Rnaset2a, 5430403G19Rik, D030047H15Rik, Gm13274, B930046K06Rik, Gm10862, Gm10792, Gm10802, Gm10532, G730003C15Rik, Runx2os1, Gm15612, Gm10856, Gm10857, Gm10685, Gm10803, Gm10723, F630028O10Rik, Gm10836, Gm10405, Gm10513, Gm10609, F630201L12Rik, 4932427H20Rik, Zfp389, Gm10763, Gm10062, Gm10714, Gm10531, Gm10876, Gm10750, Gm10433, Gm10837, Gm10647, Gm10648, Gm10650, Gm10610, F830115B05Rik, Gm10473, Gm10614, Gm10286, G730046D07Rik, Gm10287, Gm10785, Gm10183, Gm10512, 1700061E17Rik, Gm44113, Gm10579, Gm10741, Gm10827, Gm10522, Gm10536, Gm15998, Faddos, D130050E23Rik, Gm10735
14610273	Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc. Natl. Acad. Sci. U.S.A. Brian P Zambrowicz , Alejandro Abuin , Ramiro Ramirez-Solis , Lizabeth J Richter , James Piggott , Hector BeltrandelRio , Eric C Buxton , Joel Edwards , Rick A Finch , Carl J Friddle , Anupma Gupta , Gwenn Hansen , Yi Hu , Wenhu Huang , Crystal Jaing , Billie Wayne Key , Peter Kipp , Buckley Kohlhauff , Zhi-Qing Ma , Diane Markesich , Robert Payne , David G Potter , Ny Qian , Joseph Shaw , Jeff Schrick , Zheng-Zheng Shi , Mary Jean Sparks , Isaac Van Sligtenhorst , Peter Vogel , Wade Walke , Nianhua Xu , Qichao Zhu , Christophe Person , Arthur T Sands	2003-11-25	Gm14018, Notumos, Ldlrap1, Mdn1, Gm11335, Rps12-ps4, Gm17762, Umad1, BC028777, Gm13999, Gm9744, Gm11696, Dnajc3, Rsph3b, D030047H15Rik, Gm10685, Gm10876, Gm10433, Gm10706, Gm15441, Gm10787, Apela, Gm10640, Dnmt3aos, Gm10822, Gm10687, Gm10658, Gm11744, Gm10848, Gm10535, F420014N23Rik, Gm16287, Gm10463, Fmr1os, Gm12298, Tmem51os1, Gm14488, Gm15401, Gm10209, Gm1976, Gm1974, Gm1998, Gm13552, Gm10031, Gm20796, Gm11496, Gm2022, Gm2050, Gm2058, Gm13580, Gm2085, Gm2087, Gm2137, Rps16-ps2, Gm2183, Gm2225, B230206L02Rik, Gm15706, Gm2294, Gm2295, Gm2297, Tbx3os1, Gm2312, Gm2315, Gm2329, Gm10320, Lncenc1, Gm2379, Gm2381, Gm12168, Gm2419, Hrct1, Gm2428, D5Ertd605e, Gm2434, Gm16020, Gm2443, Gm2450, Gm2456, Snhg12, Gm2479, Gm13022, Gm2494, Gm12184, Gm2529, Gm2530, Gm2582, Gm12193, Gm2603, Gm2650, Rsf1os2, Gm2667, Gm13182, Gm2672, Gm2679, Gm1862, Gm2685, Gm2695, Gm2698
12904583	A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Proc. Natl. Acad. Sci. U.S.A. Jens Hansen , Thomas Floss , Petra Van Sloun , Ernst-Martin FÃ¼chtbauer , Franz Vauti , Hans-Hennig Arnold , Frank SchnÃ¼tgen , Wolfgang Wurst , Harald von Melchner , Patricia Ruiz	2003-08-19	Mdn1, Dnajc3, Gm10563, Gm9900, Gm9888, Gm10789, Gm10615, Gm2160, Gm2272, Lncenc1, Gm2381, Snhg12, Gm10232, Gm2695, Gm2701, 3830408C21Rik, Gm9825, Gm3246, Snhg15, Gm13242, Gm3325, Gm13247, Gm13157, Gm15427, Gm9800, Gm10131, Rex2, 1110002L01Rik, Gm4247, Gm14410, Gm4419, Gm9769, Gm4532, Srcap, AI662270, 9330020H09Rik, Camta1, Rcc1, Gm13225, Phactr4, Tmem64, Gpn2, AK010878, Osbpl9, 5830417I10Rik, Mir1902, Mir1949, Smpdl3b, Bsdc1, Gm13217, 1700007L15Rik, Gm17251, Gm17259, Gm13150, Gm19426, Gm19446, Gm13248, 5430416N02Rik, Gm12588, Snhg4, Gm13147, Gm19702, Gm19705, Platr22, Gm19771, Zfp534, Gm16740, AU020206, Gm20179, 2900076A07Rik, Gm15834, Gm10374, Zfp518b, Gm14401, AI480526, Tbc1d14, Akap9, Zfp513, Gm29787, Tra2a, Brk1, Mirc35hg, Phrf1, Plekha1, Numa1, Sf3b3, Champ1, Gadd45gip1, Arhgef18, Dohh, Fam192a, Taf5l, Ankrd10, Cog4, 4930512M02Rik, Gm30000, Gm30214, Gm30370, Gm31005

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