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54600 UGT1A9

54600

UGT1A9

UDP glucuronosyltransferase family 1 member A9

protein-coding

Homo sapiens

基因描述

Type Description
Definition UDP glucuronosyltransferase family 1 member A9

研究结论

Date Results Publications
2021-02-20 13:29:00 Worsening of Kidney Transplant Function During 2-Year Follow-up Is Associated With the Genetic Variants of CYP3A4, MDR1, and UGT1A9. 32222391
2020-04-11 12:13:00 Direct binding was further demonstrated by luciferase reporter gene vector carrying wild-type or binding site truncated UGT1A9 3'-UTR. MicroRNA-200a/-183 downregulated UGT1A9 expression in a dose-dependent manner and significantly reduced sorafenib beta-D-glucuronide formation in HCC cells. 30910587
2020-03-21 12:40:00 Using a graphical representation, from 708 identified polymorphisms, a reduced list of 115 candidates was obtained. Then, by analyzing each gene and the distribution of variant alleles, several candidates were highlighted such as UGT1A9, PTPN22, and ERCC5. These genes were already associated with the transport, the metabolism, and even the sensitivity to imatinib in previous studies. 31470908
2019-09-14 11:18:00 This study demonstrated that BMI influences propofol pharmacokinetics after its administration as a single intravenous injection, while UGT1A9 and CYP2B6 SNPs, other clinical factors, and hemodynamic variables do not. 29468507
2019-02-16 11:22:00 studies lead to a model for the developmental patterning of UGT1A8, UGT1A9, and UGT1A10 in hepatic and/or extrahepatic tissues involving discrete regulatory modules that may function (independently and cooperatively) in a context-dependent manner 29519853

名称对应

Type IDs
Synonymous HLUGP4, LUGP4, UDPGT, UDPGT 1-9, UGT-1I, UGT1-09, UGT1-9, UGT1.9, UGT1A9S, UGT1AI, UGT1I
Gene
UniProtKB-ID: UD19_HUMAN, Q5DSZ5_HUMAN
UniprotKB: O60656, Q5DSZ5
UniParc: UPI00042DB65D, UPI0000044213
EMBL: CH471063, BC058844, DQ364246, AC019072, AF056188, AY435144, AF297091, S55985, AK313510, AC006985, AF297093
Ensembl: ENSG00000241119
KO: hsa:54600
Nucleutide sequences
EMBL-CDS: ABC96770.1, AAH58844.1, AAG29816.1, AAB19791.2, AAC31425.1, AAG30418.1, BAG36290.1, AAR95645.1, EAW71054.1
Gene_ORFName: hCG_2039726
Ensembl_TRS: ENST00000354728
Protein sequencees
Ensembl_PRO: ENSP00000346768
RefSeq: NP_066307.1
Others
UniRef100: UniRef100_O60656
UniRef90: UniRef90_O60656
UniRef50: UniRef50_P22309
UniGene: Hs.554822
CCDS: CCDS2505.1

全选

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研究热度

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