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54598 Calcrl

54598

Calcrl

calcitonin receptor-like

protein-coding

Mus musculus

基因描述

Type Description
Definition calcitonin receptor-like

研究结论

Date Results Publications
2020-06-27 12:15:00 CGRP-CRLR/RAMP1 signal is important for stress-induced hematopoiesis. 30674976
2019-08-24 11:47:00 lymphatic insufficiency and lymphangiectasia caused by loss of lymphatic Calcrl exacerbates intestinal recovery following mucosal injury and underscores the importance of lymphatic function in promoting recovery from intestinal inflammation 28352669
2018-11-17 11:26:00 study reveals a Notch-Collagen V-Calcitonin receptor signalling cascade that maintains satellite cells in a quiescent state in a cell-autonomous fashion, and raises the possibility that similar reciprocal mechanisms act in diverse stem cell populations 29795344
2017-12-02 10:59:00 the cardiovascular response of Ramp1(-/-), Ramp2(+/-), Ramp3(-/-), Ramp1(-/-)/Ramp3(-/-) double-knockout (dKO), and Calcrl(+/-) mice to AM and CGRP were compared to wildtype mice.These results suggest that the hypotensive effect of AM is primarily mediated through the CLR/RAMP1 heterodimer, but that AM signaling via CLR/RAMP2 and CLR/RAMP3 also contributes to some hypotensive action. 27940069
2017-05-27 12:00:00 Mouse and human heart valves expressed mRNAs for the CRL ligands adrenomedullin (AM), adrenomedullin-2 (AM-2) and calcitonin gene-related peptide (CGRP) and for their receptor components, i.e., CRL and receptor-activity-modifying proteins 1-3. 27553639

名称对应

Type IDs
Synonymous AV071593, CRLR
Gene
UniProtKB-ID: CALRL_MOUSE, A2AR99_MOUSE
UniprotKB: Q9R1W5, A2AR99
UniParc: UPI0000022ACC
EMBL: AF146525, AB015595, AF209905, BC138537, BC138540
Ensembl: ENSMUSG00000059588
KO: mmu:54598
Nucleutide sequences
EMBL-CDS: AAD35021.1, AAF21037.1, BAA76492.1, AAI38538.1, AAI38541.1
Ensembl_TRS: ENSMUST00000074262, ENSMUST00000099944
Protein sequencees
Ensembl_PRO: ENSMUSP00000073875, ENSMUSP00000097527
RefSeq: XP_006499981.1, XP_036018296.1, NP_061252.2
Others
UniRef100: UniRef100_Q9R1W5
UniRef90: UniRef90_Q9R1W5
UniRef50: UniRef50_Q9R1W5
UniGene: Mm.75467
CCDS: CCDS16184.1

全选

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