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54583 EGLN1

54583

EGLN1

egl-9 family hypoxia inducible factor 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition egl-9 family hypoxia inducible factor 1

研究结论

Date Results Publications
2021-04-17 13:15:00 Label-Free Interactome Analysis Revealed an Essential Role of CUL3-KEAP1 Complex in Mediating the Ubiquitination and Degradation of PHD2. 31763849
2020-10-31 13:20:00 Hypoxia responsiveness linked variant in EGLN1 gene is enriched in oral cancer patients. 32464411
2020-09-26 13:05:00 ERK Regulates HIF1alpha-Mediated Platinum Resistance by Directly Targeting PHD2 in Ovarian Cancer. 31285371
2020-08-22 15:26:00 Tibetan PHD2, an allele with loss-of-function properties. 32414920
2020-07-25 10:32:00 PHD2 is the key regulatory enzyme of BRD4 proline hydroxylation and the modification significantly affects BRD4 interactions with key transcription factors as well as BRD4-mediated transcriptional activation. 31239290

名称对应

Type IDs
Synonymous C1orf12, ECYT3, HALAH, HIF-PH2, HIFPH2, HPH-2, HPH2, PHD2, SM20, ZMYND6
Gene
UniProtKB-ID: EGLN1_HUMAN, R4SCQ0_HUMAN
UniprotKB: Q9GZT9, R4SCQ0
UniParc: UPI0002423F19, UPI00001AA267, UPI0000050C90
EMBL: AL117352, AF246631, AF229245, CH471098, AJ310543, KC554048, AL833885, AF246630, AF277174, AF277176, AL445524
Ensembl: ENSG00000135766
KO: hsa:54583
Nucleutide sequences
EMBL-CDS: AAG34568.1, AAK07534.1, CAD38741.2, CAC42509.1, AAG33965.1, AAK07536.1, AGL94925.1, EAW69959.1
Gene_ORFName: PNAS-137, PNAS-118, hCG_1810777
Ensembl_TRS: ENST00000366641
Protein sequencees
Ensembl_PRO: ENSP00000355601
RefSeq: NP_001364189.1, NP_001364190.1, XP_024303502.1, NP_071334.1
Others
UniRef100: UniRef100_Q9GZT9
UniRef90: UniRef90_Q9GZT9
UniRef50: UniRef50_Q9GZT9
UniGene: Hs.444450
CCDS: CCDS1595.1

全选

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