| Type | Description |
|---|---|
| Definition | UDP glucuronosyltransferase family 1 member A5 |
| Date | Results | Publications |
|---|---|---|
| 2019-04-13 12:04:00 | Extensive molecular dynamics simulations revealed that the Gly259Arg mutation stabilizes helix Q through a newly formed hydrogen bonding network, which places the cofactor in a much more favorable geometry in UGT1A5*8 as compared to the wild-type. | 29710432 |
| 2010-09-15 22:06:00 | Observational study of gene-disease association. (HuGE Navigator) | 19913121 |
| 2010-09-15 22:06:00 | Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator) | 20628086 |
| 2009-12-02 21:41:00 | Observational study of gene-disease association. (HuGE Navigator) | 19898482 |
| 2008-04-03 08:26:00 | Observational study of genotype prevalence. (HuGE Navigator) | 18223459 |
| Type | IDs |
|---|---|
| Synonymous | UDPGT, UDPGT 1-5, UGT1E |
| Gene |
UniProtKB-ID:
UD15_HUMAN,
Q5DSZ9_HUMAN
UniprotKB:
P35504,
Q5DSZ9
UniParc:
UPI0000001043,
UPI00042DB65B
EMBL:
M84123,
AC114812,
M84124,
AF297093,
AY435140,
M84129,
DQ383514,
AC006985,
CH471063,
M84122
Ensembl:
ENSG00000240224
KO:
hsa:54579
|
| Nucleutide sequences |
EMBL-CDS:
AAG30421.1,
ABD42927.1,
AAA61247.1,
AAA61250.1,
EAW71059.1,
AAR95641.1
Gene_ORFName:
hCG_2039726
Ensembl_TRS:
ENST00000373414
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000362513
RefSeq:
NP_061951.1
|
| Others |
UniRef100:
UniRef100_P35504
UniRef90:
UniRef90_P22310
UniRef50:
UniRef50_P35503
UniGene:
Hs.554822
CCDS:
CCDS33404.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 29710432 |
FEBS Lett. Fan Yang , David Machalz , Sisi Wang , Zhengyi Li , Gerhard Wolber , Matthias Bureik |
2018-06-01 | - |
| 25246029 |
Genome-wide analysis of hepatic lipid content in extreme obesity. Acta Diabetol Johanna K DiStefano , Christopher Kingsley , G Craig Wood , Xin Chu , George Argyropoulos , Christopher D Still , Stefania Cotta Doné , Christophe Legendre , Waibhav Tembe , Glenn S Gerhard |
2015-04-01 |
RAMP3,
UGT1A10,
UGT1A8,
UGT1A7,
UGT1A6,
UGT1A5,
UGT1A9,
UGT1A4,
UGT1A1,
UGT1A3,
SUGP1,
PNPLA3,
SOCS2
|
| 24816252 |
An atlas of genetic influences on human blood metabolites. Nat. Genet. So-Youn Shin , Eric B Fauman , Ann-Kristin Petersen , Jan Krumsiek , Rita Santos , Jie Huang , Matthias Arnold , Idil Erte , Vincenzo Forgetta , Tsun-Po Yang , Klaudia Walter , Cristina Menni , Lu Chen , Louella Vasquez , Ana M Valdes , Craig L Hyde , Vicky Wang , Daniel Ziemek , Phoebe Roberts , Li Xi , Elin Grundberg , Multiple Tissue Human Expression Resource (MuTHER) Consortium , Melanie Waldenberger , J Brent Richards , Robert P Mohney , Michael V Milburn , Sally L John , Jeff Trimmer , Fabian J Theis , John P Overington , Karsten Suhre , M Julia Brosnan , Christian Gieger , Gabi Kastenmüller , Tim D Spector , Nicole Soranzo |
2014-06-01 | - |
| 24625756 |
Genetic determinants influencing human serum metabolome among African Americans. PLoS Genet Bing Yu , Yan Zheng , Danny Alexander , Alanna C Morrison , Josef Coresh , Eric Boerwinkle |
2014-03-01 | - |
| 24097068 |
Discovery and refinement of loci associated with lipid levels. Nat. Genet. Cristen J Willer , Ellen M Schmidt , Sebanti Sengupta , Gina M Peloso , Stefan Gustafsson , Stavroula Kanoni , Andrea Ganna , Jin Chen , Martin L Buchkovich , Samia Mora , Jacques S Beckmann , Jennifer L Bragg-Gresham , Hsing-Yi Chang , AyÅe Demirkan , Heleen M Den Hertog , Ron Do , Louise A Donnelly , Georg B Ehret , Tõnu Esko , Mary F Feitosa , Teresa Ferreira , Krista Fischer , Pierre Fontanillas , Ross M Fraser , Daniel F Freitag , Deepti Gurdasani , Kauko Heikkilä , Elina Hyppönen , Aaron Isaacs , Anne U Jackson , à sa Johansson , Toby Johnson , Marika Kaakinen , Johannes Kettunen , Marcus E Kleber , Xiaohui Li , Jian'an Luan , Leo-Pekka Lyytikäinen , Patrik K E Magnusson , Massimo Mangino , Evelin Mihailov , May E Montasser , Martina Müller-Nurasyid , Ilja M Nolte , Jeffrey R O'Connell , Cameron D Palmer , Markus Perola , Ann-Kristin Petersen , Serena Sanna , Richa Saxena , Susan K Service , Sonia Shah , Dmitry Shungin , Carlo Sidore , Ci Song , Rona J Strawbridge , Ida Surakka , Toshiko Tanaka , Tanya M Teslovich , Gudmar Thorleifsson , Evita G Van den Herik , Benjamin F Voight , Kelly A Volcik , Lindsay L Waite , Andrew Wong , Ying Wu , Weihua Zhang , Devin Absher , Gershim Asiki , Inês Barroso , Latonya F Been , Jennifer L Bolton , Lori L Bonnycastle , Paolo Brambilla , Mary S Burnett , Giancarlo Cesana , Maria Dimitriou , Alex S F Doney , Angela Döring , Paul Elliott , Stephen E Epstein , Gudmundur Ingi Eyjolfsson , Bruna Gigante , Mark O Goodarzi , Harald Grallert , Martha L Gravito , Christopher J Groves , Göran Hallmans , Anna-Liisa Hartikainen , Caroline Hayward , Dena Hernandez , Andrew A Hicks , Hilma Holm , Yi-Jen Hung , Thomas Illig , Michelle R Jones , Pontiano Kaleebu , John J P Kastelein , Kay-Tee Khaw , Eric Kim , Norman Klopp , Pirjo Komulainen , Meena Kumari , Claudia Langenberg , Terho Lehtimäki , Shih-Yi Lin , Jaana Lindström , Ruth J F Loos , François Mach , Wendy L McArdle , Christa Meisinger , Braxton D Mitchell , Gabrielle Müller , Ramaiah Nagaraja , Narisu Narisu , Tuomo V M Nieminen , Rebecca N Nsubuga , Isleifur Olafsson , Ken K Ong , Aarno Palotie , Theodore Papamarkou , Cristina Pomilla , Anneli Pouta , Daniel J Rader , Muredach P Reilly , Paul M Ridker , Fernando Rivadeneira , Igor Rudan , Aimo Ruokonen , Nilesh Samani , Hubert Scharnagl , Janet Seeley , Kaisa Silander , Alena StanÄáková , Kathleen Stirrups , Amy J Swift , Laurence Tiret , Andre G Uitterlinden , L Joost van Pelt , Sailaja Vedantam , Nicholas Wainwright , Cisca Wijmenga , Sarah H Wild , Gonneke Willemsen , Tom Wilsgaard , James F Wilson , Elizabeth H Young , Jing Hua Zhao , Linda S Adair , Dominique Arveiler , Themistocles L Assimes , Stefania Bandinelli , Franklyn Bennett , Murielle Bochud , Bernhard O Boehm , Dorret I Boomsma , Ingrid B Borecki , Stefan R Bornstein , Pascal Bovet , Michel Burnier , Harry Campbell , Aravinda Chakravarti , John C Chambers , Yii-Der Ida Chen , Francis S Collins , Richard S Cooper , John Danesh , George Dedoussis , Ulf de Faire , Alan B Feranil , Jean Ferrières , Luigi Ferrucci , Nelson B Freimer , Christian Gieger , Leif C Groop , Vilmundur Gudnason , Ulf Gyllensten , Anders Hamsten , Tamara B Harris , Aroon Hingorani , Joel N Hirschhorn , Albert Hofman , G Kees Hovingh , Chao Agnes Hsiung , Steve E Humphries , Steven C Hunt , Kristian Hveem , Carlos Iribarren , Marjo-Riitta Järvelin , Antti Jula , Mika Kähönen , Jaakko Kaprio , Antero Kesäniemi , Mika Kivimaki , Jaspal S Kooner , Peter J Koudstaal , Ronald M Krauss , Diana Kuh , Johanna Kuusisto , Kirsten O Kyvik , Markku Laakso , Timo A Lakka , Lars Lind , Cecilia M Lindgren , Nicholas G Martin , Winfried März , Mark I McCarthy , Colin A McKenzie , Pierre Meneton , Andres Metspalu , Leena Moilanen , Andrew D Morris , Patricia B Munroe , Inger Njølstad , Nancy L Pedersen , Chris Power , Peter P Pramstaller , Jackie F Price , Bruce M Psaty , Thomas Quertermous , Rainer Rauramaa , Danish Saleheen , Veikko Salomaa , Dharambir K Sanghera , Jouko Saramies , Peter E H Schwarz , Wayne H-H Sheu , Alan R Shuldiner , Agneta Siegbahn , Tim D Spector , Kari Stefansson , David P Strachan , Bamidele O Tayo , Elena Tremoli , Jaakko Tuomilehto , Matti Uusitupa , Cornelia M van Duijn , Peter Vollenweider , Lars Wallentin , Nicholas J Wareham , John B Whitfield , Bruce H R Wolffenbuttel , Jose M Ordovas , Eric Boerwinkle , Colin N A Palmer , Unnur Thorsteinsdottir , Daniel I Chasman , Jerome I Rotter , Paul W Franks , Samuli Ripatti , L Adrienne Cupples , Manjinder S Sandhu , Stephen S Rich , Michael Boehnke , Panos Deloukas , Sekar Kathiresan , Karen L Mohlke , Erik Ingelsson , Gonçalo R Abecasis , Global Lipids Genetics Consortium |
2013-11-01 | - |
| 23642732 |
Atherosclerosis Amanda J Cox , Maggie C-Y Ng , Jianzhao Xu , Carl D Langefeld , Kenneth L Koch , Paul A Dawson , J Jeffrey Carr , Barry I Freedman , Fang-Chi Hsu , Donald W Bowden |
2013-07-01 | - |
| 23371916 |
Genet. Epidemiol. Xiayun Dai , Chen Wu , Yunfeng He , Lixuan Gui , Li Zhou , Huan Guo , Jing Yuan , Binyao Yang , Jun Li , Qifei Deng , Suli Huang , Lei Guan , Die Hu , Jiang Zhu , Xinwen Min , Mingjian Lang , Dongfeng Li , Handong Yang , Frank B Hu , Dongxin Lin , Tangchun Wu , Meian He |
2013-04-01 |
SLCO1B3,
UGT1A10,
UGT1A8,
UGT1A7,
UGT1A6,
UGT1A5,
UGT1A9,
UGT1A4,
UGT1A1,
UGT1A3
|
| 23281178 |
A genome-wide assessment of variability in human serum metabolism. Hum. Mutat. Mun-Gwan Hong , Robert Karlsson , Patrik K E Magnusson , Matthew R Lewis , William Isaacs , Lilly S Zheng , Jianfeng Xu , Henrik Grönberg , Erik Ingelsson , Yudi Pawitan , Corey Broeckling , Jessica E Prenni , Fredrik Wiklund , Jonathan A Prince |
2013-03-01 |
LOC101928694,
SLCO1B1,
ACE,
ACADL,
LIPC,
FADS1,
PON1,
UGT1A10,
UGT1A8,
UGT1A7,
UGT1A6,
UGT1A5,
UGT1A9,
UGT1A4,
UGT1A1,
UGT1A3,
ACAD11,
PYROXD2,
CYP4F2
|
| 22085899 |
UGT1A1 is a major locus influencing bilirubin levels in African Americans. Eur J Hum Genet Guanjie Chen , Edward Ramos , Adebowale Adeyemo , Daniel Shriner , Jie Zhou , Ayo P Doumatey , Hanxia Huang , Michael R Erdos , Norman P Gerry , Alan Herbert , Amy R Bentley , Huichun Xu , Bashira A Charles , Michael F Christman , Charles N Rotimi |
2012-04-01 | - |
| 22511988 |
PLoS ONE Juulia Jylhävä , Leo-Pekka Lyytikäinen , Mika Kähönen , Nina Hutri-Kähönen , Johannes Kettunen , Jorma Viikari , Olli T Raitakari , Terho Lehtimäki , Mikko Hurme |
2012-01-01 |
UGT1A10,
UGT1A8,
UGT1A7,
UGT1A6,
UGT1A5,
UGT1A9,
UGT1A4,
UGT1A1,
UGT1A3
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
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| 排名 | 研究人员 | 文献 |
|---|---|---|
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