| Type | Description |
|---|---|
| Definition | UDP glucuronosyltransferase family 1 member A8 |
| Date | Results | Publications |
|---|---|---|
| 2019-02-16 11:22:00 | studies lead to a model for the developmental patterning of UGT1A8, UGT1A9, and UGT1A10 in hepatic and/or extrahepatic tissues involving discrete regulatory modules that may function (independently and cooperatively) in a context-dependent manner | 29519853 |
| 2018-12-01 11:29:00 | UGT1A8 gene polymorphisms can affect the activity of UDP glucuronosyltransferase enzyme, which may influence the elimination of mycophenolate mofetil in different patients. | 29025387 |
| 2018-08-18 11:41:00 | Polymorphism of UGT1A8 rs1042597-G variant allele is associated with colorectal cancer. | 29282011 |
| 2016-10-29 10:15:00 | the in vitro glucuronidation of raloxifene in humans and monkeys was examined using liver and intestinal microsomes and recombinant UGT enzymes (UGT1A1, UGT1A8 and UGT1A9). | 26247833 |
| 2016-10-22 12:00:00 | Data suggest UGT1A8 is involved in differential metabolism of dietary flavonoids (glucosides and aglycones); glucuronidation of flavonoid glucosides is considerably slower than glucuronidation of flavonoid aglycones in microsomes of intestine/liver. | 26317684 |
| Type | IDs |
|---|---|
| Synonymous | GNT1, UDPGT, UDPGT 1-8, UGT-1A, UGT-1H, UGT1, UGT1-01, UGT1-08, UGT1.1, UGT1.8, UGT1A, UGT1A1, UGT1A8S, UGT1H, hUG-BR1 |
| Gene |
UniProtKB-ID:
UD18_HUMAN,
Q5DSZ6_HUMAN
UniprotKB:
Q9HAW9,
Q5DSZ6
UniParc:
UPI00042DB657,
UPI0000072F75
EMBL:
AF462267,
AF465199,
CH471063,
AF462268,
AC019072,
AF465198,
AK313488,
AY435143,
AF465200,
AF030310,
DQ364251,
AF297093,
AC006985
Ensembl:
ENSG00000242366
KO:
hsa:54576
|
| Nucleutide sequences |
EMBL-CDS:
AAB84259.1,
BAG36270.1,
AAL73507.1,
AAL75963.1,
AAL73508.1,
AAL75964.1,
AAG30416.1,
AAL73506.1,
ABC96775.1,
AAR95644.1,
EAW71057.1
Gene_ORFName:
hCG_2039726
Ensembl_TRS:
ENST00000373450
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000362549
RefSeq:
NP_061949.3
|
| Others |
UniRef100:
UniRef100_Q9HAW9
UniRef90:
UniRef90_Q9HAW9
UniRef50:
UniRef50_Q9HAW9
UniGene:
Hs.554822
CCDS:
CCDS33402.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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