| Type | Description |
|---|---|
| Definition | POU class 4 homeobox 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-17 13:11:00 | POU4F1 promotes the resistance of melanoma to BRAF inhibitors through MEK/ERK pathway activation and MITF up-regulation. | 32532957 |
| 2021-03-20 13:32:00 | POU4F1 confers trastuzumab resistance in HER2-positive breast cancer through regulating ERK1/2 signaling pathway. | 32988584 |
| 2021-02-27 13:53:00 | Brn3a/Pou4f1 Functions as a Tumor Suppressor by Targeting Signaling in Thyroid Cancer. | 32474599 |
| 2019-03-23 12:16:00 | Papillary thyroid carcinoma was characterized by high expression of ESR2 and AR, which was associated with expression and content of nuclear factors Brn-3A and TRIM16. | 30488195 |
| 2017-03-25 12:41:00 | We report a case of a nine-year-old male who presented with facial nerve stimulation four years after cochlear implantation. A dilated internal auditory meatus was revealed. Genetic analysis demonstrated X-linked deafness type 2 (DFNX2) caused by a novel c.769C T nucleotide change in the POU domain, class 3, transcription factor 4 gene | 27863625 |
| Type | IDs |
|---|---|
| Synonymous | BRN3A, Oct-T1, RDC-1, brn-3A |
| Gene |
UniProtKB-ID:
PO4F1_HUMAN
UniprotKB:
Q01851
UniParc:
UPI000013DCAA,
UPI0008592511
EMBL:
U10062,
U10063,
CH471093,
L20433,
X64624,
AL445209
Ensembl:
ENSG00000152192
KO:
hsa:5457
|
| Nucleutide sequences |
EMBL-CDS:
AAA65605.1,
EAW80585.1,
AAA57161.1,
CAA45907.1
Ensembl_TRS:
ENST00000377208
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000366413
RefSeq:
NP_006228.3
|
| Others |
UniRef100:
UniRef100_Q01851
UniRef90:
UniRef90_P17208
UniRef50:
UniRef50_P17208
UniGene:
Hs.654522
CCDS:
CCDS31996.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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