| Type | Description |
|---|---|
| Definition | erythrocyte membrane protein band 4.1 like 4B |
| Date | Results | Publications |
|---|---|---|
| 2019-08-17 11:41:00 | Data show that the two Ehm2 variants appear to be differentially expressed in lung adenocarcinoma. Ehm2/1 may function as a putative tumor suppressor in the disease progression of lung adenocarcinoma, while Ehm2/2 may have an opposite function. | 30816447 |
| 2019-04-20 10:58:00 | We found that CRB3-induced proliferation is epidermal growth factor (EGF)-independent and occurs through a mechanism that involves secretion of the EGF-family ligand, amphiregulin (AREG)..We identified the FBD-containing protein, EPB41L4B, as an essential mediator of CRB3-driven proliferation and observed that the CRB3-dependent changes in endocytic trafficking were also dependent on EPB41L4B | 30440051 |
| 2015-12-05 10:26:00 | CRB3A recruits p114RhoGEF and its activator Ehm2 to the cell periphery using both functional motifs of its cytoplasmic tail and increases RhoA activation levels. | 26217016 |
| 2014-03-01 10:11:00 | Ehm2 may be an important player in the wound healing process; Ehm2 knockdown downregulates the expression of NWasp, through which it may have its effect on cellular migration | 23664528 |
| 2013-07-06 10:02:00 | (review) FERM domains are found in a wide variety of proteins, but in particular they constitute the major, and in some cases the only, recognized functional domain present in the FRMDs. | 23662806 |
| Type | IDs |
|---|---|
| Synonymous | CG1, EHM2 |
| Gene |
UniProtKB-ID:
E41LB_HUMAN,
Q59GC2_HUMAN,
Q9NSG9_HUMAN,
Q9NX84_HUMAN
UniprotKB:
Q9H329,
Q59GC2,
Q9NSG9,
Q9NX84
UniParc:
UPI0000458994,
UPI000006E21A,
UPI0000071CF9,
UPI0000458995,
UPI00004F6BDA
EMBL:
CH471105,
AB032179,
AL358815,
AL359963,
AB209187,
AL353947,
AF153416,
AF153418,
AK000388
Ensembl:
ENSG00000095203
KO:
hsa:54566
|
| Nucleutide sequences |
EMBL-CDS:
BAA96079.2,
AAG43366.1,
AAG43368.1,
BAD92424.1,
CAB89252.1,
BAA91133.1,
EAW59042.1
Gene_ORFName:
hCG_1738334
Ensembl_TRS:
ENST00000374566,
ENST00000374557
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000363685,
ENSP00000363694
RefSeq:
XP_016870303.1,
XP_011517096.1,
XP_016870304.1,
XP_016870302.1,
XP_011517093.1,
NP_001372552.1,
NP_061987.3,
NP_060894.2,
XP_011517092.1
|
| Others |
UniRef100:
UniRef100_Q59GC2,
UniRef100_Q9NX84,
UniRef100_Q9H329,
UniRef100_Q9NSG9
UniRef90:
UniRef90_Q9H329,
UniRef90_Q59GC2,
UniRef90_A0A2I3GW25,
UniRef90_Q9NSG9
UniRef50:
UniRef50_Q9NSG9,
UniRef50_Q9H329,
UniRef50_Q9JMC8,
UniRef50_G1MIA4
UniGene:
Hs.591901
CCDS:
CCDS43860.1,
CCDS43859.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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