| Type | Description |
|---|---|
| Definition | POU class 3 homeobox 4 |
| Date | Results | Publications |
|---|---|---|
| 2020-09-12 16:01:00 | BRN4 Is a Novel Driver of Neuroendocrine Differentiation in Castration-Resistant Prostate Cancer and Is Selectively Released in Extracellular Vesicles with BRN2. | 31371344 |
| 2020-06-06 12:17:00 | In this study, we identified a novel hemizygous variant, c.870G > T in the POU3F4 gene, leading to a substitution of a Lysine with an Asparagine in position 290, in two brothers from one Italian family with identical inner ear abnormalities specific to the X-linked deafness-2 (DFNX2, MIM 304400). | 31786483 |
| 2019-04-20 11:45:00 | POU3F4 gene mutation analysis will increase the success rate of stapes operations and cochlear implantations. | 30176854 |
| 2017-08-19 10:37:00 | POU3F4 mutations can be predicted by incomplete partition type III anomaly by radiological examination of the inner ear. All six of the patients showed mixed hearing loss, but none showed fluctuations in hearing, which may be related to the lack of vestibular aqueduct enlargement at the operculum. | 27577114 |
| 2017-07-01 10:36:00 | Sequencing of the entire POU3F4 gene is recommended in patients with characteristic temporal bone malformations. Results of POU3F4 mutation testing are important not only for a proper genetic counseling, but also for adequate preparation and conduction of a surgical procedure. | 27941975 |
| Type | IDs |
|---|---|
| Synonymous | BRAIN-4, BRN-4, BRN4, DFN3, DFNX2, OCT-9, OTF-9, OTF9 |
| Gene |
UniProtKB-ID:
PO3F4_HUMAN,
A0A2R8Y739_HUMAN
UniprotKB:
P49335,
A0A2R8Y739
UniParc:
UPI000045785D,
UPI0000131D8A
EMBL:
Z82170,
CH471104,
AK314967,
X82324
Ensembl:
ENSG00000196767
KO:
hsa:5456
|
| Nucleutide sequences |
EMBL-CDS:
BAG37468.1,
CAA57767.1,
EAW98577.1
Ensembl_TRS:
ENST00000373200,
ENST00000644024
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000362296,
ENSP00000495996
RefSeq:
NP_000298.3
|
| Others |
UniRef100:
UniRef100_P49335,
UniRef100_A0A2R8Y739
UniRef90:
UniRef90_P49335
UniRef50:
UniRef50_P49335
UniGene:
Hs.2229
CCDS:
CCDS14450.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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