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54552 GNL3L

54552

GNL3L

G protein nucleolar 3 like

protein-coding

Homo sapiens

基因描述

Type Description
Definition G protein nucleolar 3 like

研究结论

Date Results Publications
2017-06-24 11:33:00 GNL3L-LDOC1 interplay regulates cell proliferation through the modulation of NF-kappaB pathway during tumorigenesis. 27764577
2016-05-07 11:22:00 the present study provides evidence that GNL3L is exported from the nucleus in CRM1 dependent manner and the nuclear localization of GNL3L is important to promote 'S' phase progression during cell proliferation. 26274615
2015-04-18 13:28:00 GNL3L depletion impairs ribosome production without inducing appreciable DNA damage. During evolution, GNL3L retained the role of the ancestral gene in ribosome biosynthesis, whereas the paralogous nucleostemin acquired a novel genome-protective function. 24610951
2011-10-01 11:35:00 differences in the relative nucleostemin protein and mRNA levels may reflect the degree of proliferation of mesnchymal stem cells and can be used to characterize in vitro expansion capabilities 21063916
2011-06-25 13:06:00 GNL3L bound MDM2 in vivo, stabilizing MDM2 and preventing its ubiquitylation. GNL3L depletion upregulated specific p53 targets (Bax, 14-3-3sigma and p21). 21132010

名称对应

Type IDs
Synonymous GNL3B
Gene
UniProtKB-ID: GNL3L_HUMAN, A0A024R9Y6_HUMAN, Q05DU1_HUMAN
UniprotKB: Q9NVN8, A0A024R9Y6, Q05DU1
UniParc: UPI000006CF81, UPI0000D4912C
EMBL: AL391139, BC011720, CH471154, BC003603, AK001475
Ensembl: ENSG00000130119
KO: hsa:54552
Nucleutide sequences
EMBL-CDS: BAA91712.1, AAH11720.1, EAW93183.1, EAW93185.1, EAW93182.1, AAH03603.1
Gene_ORFName: hCG_1810878
Ensembl_TRS: ENST00000674225, ENST00000674498, ENST00000674311, ENST00000360845, ENST00000336470
Protein sequencees
Ensembl_PRO: ENSP00000501452, ENSP00000338573, ENSP00000354091, ENSP00000501411, ENSP00000501441
RefSeq: NP_061940.1, NP_001171748.1
Others
UniRef100: UniRef100_Q9NVN8, UniRef100_Q05DU1
UniRef90: UniRef90_Q9NVN8
UniRef50: UniRef50_Q9NVN8
UniGene: Hs.654677
CCDS: CCDS14360.1

全选

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