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5454 POU3F2

5454

POU3F2

POU class 3 homeobox 2

protein-coding

Homo sapiens

基因描述

Type Description
Definition POU class 3 homeobox 2

研究结论

Date Results Publications
2021-01-09 13:26:00 Unexpected High Levels of BRN2/POU3F2 Expression in Human Dermal Melanocytic Nevi. 31881210
2020-09-12 16:01:00 BRN4 Is a Novel Driver of Neuroendocrine Differentiation in Castration-Resistant Prostate Cancer and Is Selectively Released in Extracellular Vesicles with BRN2. 31371344
2020-05-30 13:30:00 Study investigated super-enhancer profiles in lung squamous cell carcinoma (LUSC) and identified a novel subtype in which SOX2 and a neural transcription factor BRN2 have key roles in determining its distinctive differentiation state. BRN2 serves as an interacting partner for SOX2 in this novel subtype, instead of p63 in the classical subtype of LUSC. 31551362
2019-10-12 11:16:00 POU3F2 may be a key regulator of gene expression in this disease-associated gene coexpression module. 30545964
2019-06-01 10:29:00 These results suggest that the proliferative population within melanoma tumors express MITF, and both MITF and BRN2 are important for metastatic growth in vivo. This finding highlights the importance of BRN2 and MITF expression in development of melanoma metastasis. 28883623

名称对应

Type IDs
Synonymous BRN2, N-Oct3, OCT7, OTF-7, OTF7, POUF3, brn-2, oct-7
Gene
UniProtKB-ID: PO3F2_HUMAN
UniprotKB: P20265
UniParc: UPI000016A1E7, UPI0000D7A4F3, UPI0000D7A4F4
EMBL: BC051699, AL022395, Z11933, L37868
Ensembl: ENSG00000184486
KO: hsa:5454
Nucleutide sequences
EMBL-CDS: AAB59611.1, AAH51699.2, CAA77990.1
Ensembl_TRS: ENST00000328345
Protein sequencees
Ensembl_PRO: ENSP00000329170
RefSeq: NP_005595.2
Others
UniRef100: UniRef100_P20265
UniRef90: UniRef90_P20265
UniRef50: UniRef50_P20265
UniGene: Hs.182505
CCDS: CCDS5040.1

全选

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研究热度

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