| Type | Description |
|---|---|
| Definition | roundabout guidance receptor 4 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-16 15:59:00 | Nuclear Localization of Robo is Associated with Better Survival in Bladder Cancer. | 30019121 |
| 2020-12-05 13:03:00 | PRC2 Components Maintain DNA Hypermethylation of the Upstream Promoter and Regulate Robo4 Expression in Endothelial Cells. | 32238717 |
| 2020-09-12 15:58:00 | Regulatory mechanisms of Robo4 and their effects on angiogenesis. | 31160487 |
| 2020-05-30 11:21:00 | VEGF and Robo4 were co-expressed in FVMs from proliferative diabetic retinopathy (PDR) patients. In the early stages, VEGF was upregulated and contributed to retinopahy development, whereas, in the late stage, VEGF and Robo4 worked together to aggravate disease progression. However, miR-15a could downregulate VEGF and Robo4 to ameliorate Diabetic retinopathy development. | 30980286 |
| 2020-05-23 10:46:00 | In human brain endothelial cells that were damaged by hypoxia plus IL-1beta, treatment with recombinant ANXA2 (rA2) rescued the expression of junctional proteins and decreased trans-endothelial permeability. The protective effects were mediated in part by interactions with F-actin and VE-cadherin, and the ability of rA2 to modulate signaling via Robo4 -paxillin- ARF6. | 29786451 |
| Type | IDs |
|---|---|
| Synonymous | ECSM4, MRB |
| Gene |
UniProtKB-ID:
ROBO4_HUMAN,
B4DYV8_HUMAN
UniprotKB:
Q8WZ75,
B4DYV8
UniParc:
UPI00001FA60C,
UPI00017A8554,
UPI0000140754,
UPI000004A023
EMBL:
BC111562,
AY358083,
AK027852,
AK302628,
AK000805,
AK289769,
BC111748,
AK025195,
BC039602,
AF361473,
AK074163,
AP003501,
BC064643
Ensembl:
ENSG00000154133
KO:
hsa:54538
|
| Nucleutide sequences |
EMBL-CDS:
BAB84989.1,
AAH64643.1,
BAB15082.1,
BAB55411.1,
AAI11563.1,
AAL31867.1,
AAH39602.1,
BAA91382.1,
AAQ88450.1,
AAI11749.1,
BAF82458.1,
BAG63870.1
Gene_ORFName:
UNQ421/PRO3674
Ensembl_TRS:
ENST00000306534,
ENST00000533054
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000304945,
ENSP00000437129
RefSeq:
XP_006718924.1,
NP_061928.4,
XP_011541177.1,
NP_001288017.1
|
| Others |
UniRef100:
UniRef100_Q8WZ75
UniRef90:
UniRef90_Q8WZ75
UniRef50:
UniRef50_Q8WZ75
UniGene:
Hs.524121
CCDS:
CCDS8455.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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