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54518 APBB1IP

54518

APBB1IP

amyloid beta precursor protein binding family B member 1 interacting protein

protein-coding

Homo sapiens

基因描述

Type Description
Definition amyloid beta precursor protein binding family B member 1 interacting protein

研究结论

Date Results Publications
2021-02-27 13:49:00 RIAM-VASP Module Relays Integrin in Outside-In Signaling Driving Particle Engulfment. 32397169
2020-08-29 12:49:00 Talin dissociates from RIAM and associates to vinculin sequentially in response to the actomyosin force. 32561773
2019-05-04 12:33:00 We solved the crystal structure of IN-RA-PH to a resolution of 2.4-A. The structure reveals that the IN segment associates with the RA segment and thereby suppresses RIAM:RAP1 association. This autoinhibitory configuration of RIAM can be released by phosphorylation at Tyr45 in the IN segment. 30733287
2018-01-13 10:03:00 Authors provide an overview of the structure and interactions of RIAM and discuss the implications of RIAM functions in innate and adaptive immunity and cancer. [Review] 28831022
2017-08-05 11:15:00 The Rap1-RIAM-talin axis of integrin activation and blood cell function 27207789

名称对应

Type IDs
Synonymous INAG1, PREL1, RARP1, RIAM
Gene
UniProtKB-ID: AB1IP_HUMAN
UniprotKB: Q7Z5R6
UniParc: UPI000007422E, UPI00001AF165
EMBL: BC035636, CH471072, BC054516, AL160287, AB085852, AL355798, AY152730
Ensembl: ENSG00000077420
KO: hsa:54518
Nucleutide sequences
EMBL-CDS: AAH54516.1, AAN75525.1, AAH35636.1, EAW86097.1, BAC41256.1
Ensembl_TRS: ENST00000356785, ENST00000376236
Protein sequencees
Ensembl_PRO: ENSP00000349237, ENSP00000365411
RefSeq: NP_061916.3, XP_006717514.1, XP_011517816.1
Others
UniRef100: UniRef100_Q7Z5R6
UniRef90: UniRef90_Q7Z5R6
UniRef50: UniRef50_Q7Z5R6
UniGene: Hs.310421
CCDS: CCDS31167.1

全选

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研究热度

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