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54502 RBM47

54502

RBM47

RNA binding motif protein 47

protein-coding

Homo sapiens

基因描述

Type Description
Definition RNA binding motif protein 47

研究结论

Date Results Publications
2020-02-01 11:38:00 The first RNA recognition motif (RRM) domain of RBM47 is critical in the regulation of alternative splicing and its recognition to pre-mRNA of TJP1. Furthermore, the TJP1-alpha- isoform enhances the assembly of actin stress fibers, thereby promoting cellular migration in a wound healing assay, providing a basis for studies related to the modulation of epithelial-to-mesenchymal transition via alternative splicing. 31358901
2020-01-18 10:19:00 Results identified and confirmed to have downregulated gene expression of SFRP5 in sporadic nonfunctioning pancreatic neuroendocrine tumors (NFPanNETs) and CDCA7L and RBM47 in MEN1-related NFPanNETs. 30620390
2019-02-16 11:02:00 miR-25 could directly target the RNA-binding motif protein 47 (RBM47). RBM47 is a promising target for the treatment of melanoma. 30403177
2019-02-02 10:08:00 Results show that down-regulation of RBM47 is associated with and functionally important for colorectal cancer (CRC) progression. Therefore, detection of RBM47 down-regulation may serve as a new prognostic marker for CRC and might represent an important diagnostic option to identify patients with poor prognosis. 28680090
2017-09-02 11:39:00 Our findings, together with the enhanced tumor formation and metastasis of xenografted mice by knockdown of the RBM47 expression, suggested tumor-suppressive roles for RBM47 through the inhibition of Nrf2 activity 26923328

名称对应

Type IDs
Synonymous NET18
Gene
UniProtKB-ID: RBM47_HUMAN
UniprotKB: A0AV96
UniParc: UPI000020BBEC, UPI0000140649
EMBL: BC126261, AF262323, AC098869, AC112717, BC034402, AK000280, AF261889
Ensembl: ENSG00000163694
KO: hsa:54502
Nucleutide sequences
EMBL-CDS: AAI26262.1, AAM21972.1, BAA91049.1, AAM21973.1, AAH34402.1
Ensembl_TRS: ENST00000381795, ENST00000381793, ENST00000295971
Protein sequencees
Ensembl_PRO: ENSP00000371212, ENSP00000295971, ENSP00000371214
RefSeq: XP_024309866.1, NP_061900.2, NP_001092104.1, XP_005248166.1, XP_016863796.1, NP_001358042.1, XP_016863795.1, XP_016863799.1, XP_016863798.1, XP_016863793.1, XP_005248160.1, XP_011512009.1, XP_005248165.1, NP_001358043.1, XP_016863797.1, XP_011512010.1
Others
UniRef100: UniRef100_A0AV96
UniRef90: UniRef90_A0AV96
UniRef50: UniRef50_A0AV96
UniGene: Hs.518727
CCDS: CCDS3460.1, CCDS43223.1

全选

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