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54498 SMOX

54498

SMOX

spermine oxidase

protein-coding

Homo sapiens

基因描述

Type Description
Definition spermine oxidase

研究结论

Date Results Publications
2019-07-20 10:14:00 SMOX plays a central role in the formation of bile canalicular lumen in liver cells by activating Akt pathway through acrolein production. 29093526
2017-12-30 11:04:00 Data suggest that intermolecular disulfide bond links spermine oxidase (SMOX) molecules to form the homodimer and plays a critical role in the stabilization of the overall three-dimensional SMOX structure. 29138259
2017-09-09 10:14:00 These results indicate a protective role for miR-124 through the inhibition of SMOX-mediated DNA damage in the etiology of H. pylori-associated gastric cancer. 27041578
2016-07-30 11:10:00 effect of Tat on Nrf2 activation in human neuroblastoma cells and the role of NMDA receptor and spermine oxidase on Tat-induced nuclear factor erythroid 2-related factor 2 (Nrf2) activation 26895301
2015-09-26 12:19:00 During H. pylori infection, the enzyme spermine oxidase (SMOX) is induced, which generates hydrogen peroxide from the catabolism of the polyamine spermine, and increases gastric cancer risk. 25174398

名称对应

Type IDs
Synonymous C20orf16, PAO, PAO-1, PAO1, PAOH, PAOH1, SMO
Gene
UniProtKB-ID: SMOX_HUMAN
UniprotKB: Q9NWM0
UniParc: UPI000006CE86, UPI0000140611, UPI0000160842, UPI000006D804, UPI00003BF77A, UPI0000EE6E63
EMBL: AL162058, AY033889, BC000669, AK025938, CH471133, AY358104, AF519179, AK000753, AY033890, EF032141, AL121675, AY033891
Ensembl: ENSG00000088826
KO: hsa:54498
Nucleutide sequences
EMBL-CDS: AAH00669.1, AAK55763.1, AAQ88471.1, EAX10462.1, ABM01872.1, AAK55764.1, EAX10460.1, EAX10457.1, CAB82396.1, AAN77119.1, BAB15288.1, AAK55765.1, BAA91360.1, EAX10461.1, EAX10458.1, EAX10459.1
Gene_ORFName: UNQ3039/PRO9854
Ensembl_TRS: ENST00000379460, ENST00000621355, ENST00000305958, ENST00000346595, ENST00000339123, ENST00000278795
Protein sequencees
Ensembl_PRO: ENSP00000368773, ENSP00000478305, ENSP00000344595, ENSP00000341775, ENSP00000307252, ENSP00000278795
RefSeq: NP_787035.1, NP_001257620.1, NP_787033.1, XP_011527563.1, NP_787036.1, NP_787034.1
Others
UniRef100: UniRef100_Q9NWM0
UniRef90: UniRef90_Q9NWM0
UniRef50: UniRef50_Q9NWM0
UniGene: Hs.433337
CCDS: CCDS74702.1, CCDS13078.1, CCDS13076.1, CCDS13077.1, CCDS13075.1

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