| Type | Description |
|---|---|
| Definition | IQ motif containing GTPase activating protein 2 |
| Date | Results | Publications |
|---|---|---|
| 2018-04-14 10:03:00 | The exacerbated mast cell responses observed in the absence of Dnmt3a were recapitulated or enhanced by treatment with the demethylating agent 5-aza-2'-deoxycytidine as well as by down-modulation of Dnmt1 expression. These effects were in part mediated by the dysregulated expression of the scaffold protein IQGAP2. | 28167789 |
| 2017-10-07 12:07:00 | found a hypomethylated region mapping to Iqgap2 (IQ motif-containing GTPase activating protein 2) and F2rl2 | 28179424 |
| 2016-04-09 10:33:00 | Data show that complete loss of IQ motif-containing GTPase-activating protein 2 (IQGAP2) gene leads to protection from dextran sulfate sodium (DSS)-induced colitis. | 26047140 |
| 2014-04-19 11:18:00 | Transcript profiling identifies iqgap2(-/-) mouse as a model for advanced human hepatocellular carcinoma. | 23951254 |
| 2012-09-15 11:12:00 | Phosphoinositide module is defined by a C-terminal 105-107 amino acid region of which IQGAP1 and -2, but not IQGAP3, binds preferentially to phosphatidylinositol 3,4,5-trisphosphate (PtdInsP(3)). | 22493426 |
| Type | IDs |
|---|---|
| Synonymous | 4933417J23Rik, A630053O10, AI788777 |
| Gene |
UniProtKB-ID:
IQGA2_MOUSE
UniprotKB:
Q3UQ44
UniParc:
UPI0000E86CA8
EMBL:
AK142813,
AK147360
Ensembl:
ENSMUSG00000021676
KO:
mmu:544963
|
| Nucleutide sequences |
EMBL-CDS:
BAE25199.1
Ensembl_TRS:
ENSMUST00000068603
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000067685
RefSeq:
XP_036013984.1,
NP_081987.1,
XP_036013985.1
|
| Others |
UniRef100:
UniRef100_Q3UQ44
UniRef90:
UniRef90_Q3UQ44
UniRef50:
UniRef50_Q3UQ44
UniGene:
Mm.38878
CCDS:
CCDS36753.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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