| Type | Description |
|---|---|
| Definition | thioredoxin related transmembrane protein 3 |
| Date | Results | Publications |
|---|---|---|
| 2019-12-28 10:52:00 | Data show that TMX3 expression is upregulated in melanoma cell lines and patient samples. TMX knockdown altered mitochondrial organization, enhanced bioenergetics, and elevated mitochondrial- and NOX4-derived The TMX-knockdown-induced oxidative stress suppressed melanoma proliferation, migration, and xenograft tumor growth by inhibiting NFAT1. TMX1 is associated with poor disease outcome. | 31304984 |
| 2010-09-13 11:17:00 | Haploinsufficiency for TMX3 results in a small eye phenotype and represents a novel genetic cause of microphthalmia and coloboma. | 20485507 |
| 2010-01-21 00:00:00 | analysis of TMX3 interdomain stabilization of the N-terminal redox-active domain | 17881353 |
| 2010-01-21 00:00:00 | TMX3 is a thioredoxin-related transmembrane protein of the endoplasmic reticulum | 15623505 |
| 2009-04-01 21:31:00 | Observational study of gene-disease association. (HuGE Navigator) | 19240061 |
| Type | IDs |
|---|---|
| Synonymous | PDIA13, TXNDC10 |
| Gene |
UniProtKB-ID:
TMX3_HUMAN
UniprotKB:
Q96JJ7
UniParc:
UPI000004A093,
UPI000040B9F3
EMBL:
AB058733,
AK000800,
AK122715,
BC093792,
BC093794,
BX647846,
BC032325
Ensembl:
ENSG00000166479
KO:
hsa:54495
|
| Nucleutide sequences |
EMBL-CDS:
AAH93792.1,
BAA91381.1,
BAG53687.1,
AAH32325.1,
BAB47459.1,
AAH93794.1
Ensembl_TRS:
ENST00000562706,
ENST00000299608
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000457262,
ENSP00000299608
RefSeq:
NP_001337443.1,
NP_001337441.1,
NP_001337445.1,
XP_011524336.1,
NP_001337442.1,
NP_001337446.1,
XP_011524337.1,
NP_001337444.1,
NP_061895.3
|
| Others |
UniRef100:
UniRef100_Q96JJ7
UniRef90:
UniRef90_Q96JJ7
UniRef50:
UniRef50_Q96JJ7
UniGene:
Hs.440534
CCDS:
CCDS32840.1,
CCDS86680.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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