| Type | Description |
|---|---|
| Definition | POU class 1 homeobox 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-08-01 14:20:00 | Data identify POU1F1 as a transcription factor that regulates TFPI transcription in response to ADTRP, and link POU1F1 variants to risk of CAD for the first time. | 32445923 |
| 2020-04-18 10:03:00 | Through the release of CXCL12, Pit-1 in tumor cells was found to mediate the recruitment and polarization of macrophages into tumor-associated macrophages (TAMs). In turn, TAMs collaborated with tumor cells to increase tumor growth, angiogenesis, extravasation and metastasis to lung. | 31292963 |
| 2020-03-14 10:49:00 | Transgenic mouse model for conditional expression of influenza hemagglutinin-tagged human SLC20A1/PIT1 has been reported. | 31613887 |
| 2019-08-17 12:32:00 | POU1F1 c.605delC mutation codes for a truncated protein with reduced transactivation capacity on its downstream effectors, viz., growth hormone (GH) and prolactin (PRL) causing severe combined pituitary hormone deficiency. | 31022740 |
| 2019-07-27 13:14:00 | Results suggest that transcriptional regulation of macrophage migration inhibitory factor (MIF) and pursuing pituitary-specific positive transcription factor 1 (Pit-1) as a therapeutic target to treat MIF-mediated inflammatory disorders. | 29186613 |
| Type | IDs |
|---|---|
| Synonymous | CPHD1, GHF-1, PIT1, POU1F1a, Pit-1 |
| Gene |
UniProtKB-ID:
PIT1_HUMAN
UniprotKB:
P28069
UniParc:
UPI0000131B22,
UPI000002B11B
EMBL:
X62429,
X77223,
D12892,
X72215,
D11333,
L18781,
D10216,
X77224
Ensembl:
ENSG00000064835
KO:
hsa:5449
|
| Nucleutide sequences |
EMBL-CDS:
CAA51017.1,
BAA34536.1,
CAA44295.1,
CAA54440.2,
AAA60093.1,
CAA54441.1,
BAA01068.1,
BAA02291.1
Ensembl_TRS:
ENST00000344265,
ENST00000350375
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000263781,
ENSP00000342931
RefSeq:
NP_001116229.1,
NP_000297.1
|
| Others |
UniRef100:
UniRef100_P28069
UniRef90:
UniRef90_P28069
UniRef50:
UniRef50_P28069
UniGene:
Hs.591654
CCDS:
CCDS46873.1,
CCDS2919.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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