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54476 RNF216

54476

RNF216

ring finger protein 216

protein-coding

Homo sapiens

基因描述

Type Description
Definition ring finger protein 216

研究结论

Date Results Publications
2020-06-13 11:48:00 An essential function of RNF216 in spermatogenesis and male fertility and suggest a critical role for RNF216 in human gonadal development. 30649198
2020-05-16 12:44:00 that TLR8 proteasomal disposal through RNF216 in response to RNA ligands regulates TLR8 cellular concentrations 31385713
2019-09-07 10:49:00 ICM inhibited autophagy by inhibiting nucleocytoplasmic translocation of HMGB1 and by increasing Beclin 1 ubiquitylation for degradation by enhancing the interaction between Beclin 1 and E3 ubiquitin ligase RNF216 29361549
2018-02-10 11:52:00 RNF216 is a potential biomarker and novel therapeutic target for inhibiting colorectal carcinoma development and progression. 27203674
2017-06-24 10:14:00 missense mutations in TRIAD3 abolished the interaction of TRIAD3A with Arc, disrupting Arc ubiquitination, and consequently Arc degradation. 27995769

名称对应

Type IDs
Synonymous CAHH, TRIAD3, U7I1, UBCE7IP1, ZIN
Gene
UniProtKB-ID: RN216_HUMAN, A8K8N1_HUMAN
UniprotKB: Q9NWF9, A8K8N1
UniParc: UPI000020EA98, UPI000013F5B3, UPI00015DAA53, UPI000013D69A
EMBL: AF513718, BC000787, AY177398, BX537406, AY177397, AY062174, BC063825, AC008167, AF513717, AY177396, AK000916, AF228527, AK292396
Ensembl: ENSG00000011275
KO: hsa:54476
Nucleutide sequences
EMBL-CDS: BAA91422.1, AAP47175.1, AAO60361.1, AAF36723.1, AAS07532.1, CAD97648.1, AAO60362.1, AAL38043.1, AAH63825.1, AAH00787.2, AAP47174.1, AAO60363.1, BAF85085.1
Ensembl_TRS: ENST00000389902, ENST00000425013
Protein sequencees
Ensembl_PRO: ENSP00000374552, ENSP00000404602
RefSeq: XP_024302573.1, NP_996994.1, XP_024302575.1, XP_011513738.1, XP_024302574.1, XP_016867853.1, XP_005249842.1, NP_996999.1, NP_001364085.1
Others
UniRef100: UniRef100_Q9NWF9, UniRef100_A8K8N1
UniRef90: UniRef90_Q9NWF9
UniRef50: UniRef50_Q9NWF9
UniGene: Hs.487458, Hs.689456
CCDS: CCDS34594.1, CCDS34595.1

全选

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