Type | Description |
---|---|
Definition | toll interacting protein |
Date | Results | Publications |
---|---|---|
2020-05-02 10:09:00 | TOLLIP decreases lung-specific TLR responses to increase susceptibility to Legionella pneumophila pneumonia. | 31462698 |
2020-04-18 11:46:00 | our findings reveal that resting-state STING protein level is strictly regulated by a constant tug-of-war between 'stabilizer' TOLLIP and 'degrader' IRE1alpha-lysosome that together maintain tissue immune homeostasis | 31932809 |
2019-11-23 11:12:00 | Tollip protects against neointima formation by negatively regulating vascular smooth muscle cell proliferation, dedifferentiation, and migration in an Akt-dependent manner. | 29887521 |
2019-09-14 10:37:00 | IL-13-treated Tollip-knockout (KO) mice exihibt increased lung eosinophilic inflammation and eotaxin-2 levels. IL-13- treated Tollip KO macrophages, in the absence and particularly in the presence of IL-33, increases expression of IL-33 receptor ST2L and CCL24, which is in part dependent on enhanced activation of interleukin (IL)-1 receptor-associated kinase 1 and signal transducer and activator of transcription 6. | 29393212 |
2019-06-22 10:30:00 | L. donovani exploited the multitasking function of Tollip for its own establishment through downregulating IL-1R1/TLR signaling in macrophages. | 29907707 |
Type | IDs |
---|---|
Synonymous | 4930403G24Rik, 4931428G15Rik |
Gene |
UniProtKB-ID:
TOLIP_MOUSE,
F7AT44_MOUSE
UniprotKB:
Q9QZ06,
F7AT44
UniParc:
UPI00001F5974,
UPI0000004070
EMBL:
AJ242971,
AL772165,
AK016482,
BC062139,
AK161312,
AK015062,
AK045422,
AK049263
Ensembl:
ENSMUSG00000025139
KO:
mmu:54473
|
Nucleutide sequences |
EMBL-CDS:
BAE36316.1,
BAB30262.1,
CAB58121.1,
BAC32357.1,
BAC33643.1,
AAH62139.1
Ensembl_TRS:
ENSMUST00000001950,
ENSMUST00000130439
|
Protein sequencees |
Ensembl_PRO:
ENSMUSP00000001950,
ENSMUSP00000117938
RefSeq:
NP_001334491.1,
NP_076253.1
|
Others |
UniRef100:
UniRef100_Q9QZ06,
UniRef100_F7AT44
UniRef90:
UniRef90_A2RUW1
UniRef50:
UniRef50_A2RUW1
UniGene:
Mm.103551
CCDS:
CCDS22020.1
|
{{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
---|---|---|---|---|---|---|---|---|
Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
暂无数据
排名 | 科研单位 | 文献 |
---|---|---|
{{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
排名 | 研究人员 | 文献 |
---|---|---|
{{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员