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54473 Tollip

54473

Tollip

toll interacting protein

protein-coding

Mus musculus

基因描述

Type Description
Definition toll interacting protein

研究结论

Date Results Publications
2020-05-02 10:09:00 TOLLIP decreases lung-specific TLR responses to increase susceptibility to Legionella pneumophila pneumonia. 31462698
2020-04-18 11:46:00 our findings reveal that resting-state STING protein level is strictly regulated by a constant tug-of-war between 'stabilizer' TOLLIP and 'degrader' IRE1alpha-lysosome that together maintain tissue immune homeostasis 31932809
2019-11-23 11:12:00 Tollip protects against neointima formation by negatively regulating vascular smooth muscle cell proliferation, dedifferentiation, and migration in an Akt-dependent manner. 29887521
2019-09-14 10:37:00 IL-13-treated Tollip-knockout (KO) mice exihibt increased lung eosinophilic inflammation and eotaxin-2 levels. IL-13- treated Tollip KO macrophages, in the absence and particularly in the presence of IL-33, increases expression of IL-33 receptor ST2L and CCL24, which is in part dependent on enhanced activation of interleukin (IL)-1 receptor-associated kinase 1 and signal transducer and activator of transcription 6. 29393212
2019-06-22 10:30:00 L. donovani exploited the multitasking function of Tollip for its own establishment through downregulating IL-1R1/TLR signaling in macrophages. 29907707

名称对应

Type IDs
Synonymous 4930403G24Rik, 4931428G15Rik
Gene
UniProtKB-ID: TOLIP_MOUSE, F7AT44_MOUSE
UniprotKB: Q9QZ06, F7AT44
UniParc: UPI00001F5974, UPI0000004070
EMBL: AJ242971, AL772165, AK016482, BC062139, AK161312, AK015062, AK045422, AK049263
Ensembl: ENSMUSG00000025139
KO: mmu:54473
Nucleutide sequences
EMBL-CDS: BAE36316.1, BAB30262.1, CAB58121.1, BAC32357.1, BAC33643.1, AAH62139.1
Ensembl_TRS: ENSMUST00000001950, ENSMUST00000130439
Protein sequencees
Ensembl_PRO: ENSMUSP00000001950, ENSMUSP00000117938
RefSeq: NP_001334491.1, NP_076253.1
Others
UniRef100: UniRef100_Q9QZ06, UniRef100_F7AT44
UniRef90: UniRef90_A2RUW1
UniRef50: UniRef50_A2RUW1
UniGene: Mm.103551
CCDS: CCDS22020.1

全选

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