| Type | Description |
|---|---|
| Definition | mitochondrial elongation factor 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-23 13:01:00 | An epigenetic increase in mitochondrial fission by MiD49 and MiD51 regulates the cell cycle in cancer: Diagnostic and therapeutic implications. | 32068312 |
| 2020-07-18 11:54:00 | The study uncovers a bridging role of MIEF1 integrating cell death and mitophagy, unlikely dependent on mitochondrial dynamics, implying new insights to mechanisms determining cellular fate. | 30894073 |
| 2020-06-13 11:22:00 | We found that the receptors mitochondrial fission factor (Mff) and mitochondrial elongation factor 1/2 (MIEF1/2) interact with and recruit Drp1(pS637) to mitochondria and that elevated Mff or MIEF levels promote Drp1(pS637) accumulation on mitochondria. We also noted that protein kinase A which mediates phosphorylation of Drp1 on Ser-637, is partially present on mitochondria and interacts with both MIEFs and Mff | 31533986 |
| 2019-10-05 10:37:00 | In health, MiD51 regulate Drp1-mediated fission, whereas in disease, epigenetic upregulation of MiD51 increases mitotic fission, which drives pathological proliferation and apoptosis resistance | 29431643 |
| 2019-07-13 12:22:00 | Loss of mitochondrial elongation factor 1 microprotein (MIEF1-MP) decreases the mitochondrial translation rate, while an elevated level of MIEF1-MP increases the translation rate | 30215512 |
| Type | IDs |
|---|---|
| Synonymous | AltMIEF1, HSU79252, MID51, MIEF1-MP, SMCR7L, dJ1104E15.3 |
| Gene |
UniProtKB-ID:
MID51_HUMAN,
A0A024R1L3_HUMAN,
Q9H0J7_HUMAN,
B0QY95_HUMAN
UniprotKB:
Q9NQG6,
A0A024R1L3,
Q9H0J7,
B0QY95
UniParc:
UPI0000401E96,
UPI0000072474,
UPI000013C6CC,
UPI000006FEB4
EMBL:
AL022312,
AL136768,
AL365515,
AK290954,
AL834205,
BC002587,
CH471095,
BC008327
Ensembl:
ENSG00000100335
KO:
hsa:54471
|
| Nucleutide sequences |
EMBL-CDS:
CAB97211.1,
AAH02587.2,
BAF83643.1,
EAW60335.1,
AAH08327.1,
CAD38892.2,
EAW60336.1,
EAW60337.1,
CAB66702.1,
EAW60338.1
Gene_ORFName:
hCG_41725,
hCG_41725
Ensembl_TRS:
ENST00000325301,
ENST00000404569,
ENST00000433117,
ENST00000428069,
ENST00000402881
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000385191,
ENSP00000413730,
ENSP00000404096,
ENSP00000327124,
ENSP00000385110
RefSeq:
XP_011528540.1,
XP_011528538.1,
NP_061881.2,
XP_016884327.1,
NP_001291493.1,
XP_011528539.1
|
| Others |
UniRef100:
UniRef100_Q9H0J7,
UniRef100_Q9NQG6,
UniRef100_B0QY95
UniRef90:
UniRef90_Q9NQG6,
UniRef90_B0QY95
UniRef50:
UniRef50_Q9NQG6
UniGene:
Hs.728085
CCDS:
CCDS13995.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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