| Type | Description |
|---|---|
| Definition | fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) |
| Date | Results | Publications |
|---|---|---|
| 2020-07-04 11:28:00 | dnVegfaa and sFlt1 have different roles in zebrafish pancreatic vasculature and islet development | 31597659 |
| 2018-12-22 11:21:00 | sFlt1 role in the venous sprouting and spinal cord vascularization. | 28071661 |
| 2017-11-26 00:32:00 | we determined that radial glia control this process via the Vegf decoy receptor sFlt1: sflt1 mutants exhibit the venous over-sprouting observed in radial glia-ablated larvae, and sFlt1 overexpression rescues it. Genetic mosaic analyses show that sFlt1 function in trunk endothelial cells can limit their over-sprouting. | 27852438 |
| 2015-03-21 10:48:00 | Flt1-tyrosine kinase (TK) activity contributed significantly in endothelial cells survival and vascular development during embryo angiogenesis in zebrafish by engaging PI3K/Akt pathway. | 25450186 |
| 2013-09-28 11:51:00 | Elevated Notch signaling downstream of perturbed VEGF signaling contributes to aberrant flt-1(-/-) blood vessel formation. | 23744993 |
| Type | IDs |
|---|---|
| Synonymous | VEGFR1, flt1b, sFlt1 |
| Gene |
UniProtKB-ID:
B3DKP1_DANRE,
F1QBD0_DANRE
UniprotKB:
B3DKP1,
F1QBD0
UniParc:
UPI0000567600,
UPI0001E9027A
EMBL:
BC163921,
CR352265,
BX571696
Ensembl:
ENSDARG00000019371,
ENSDARG00000111797
KO:
dre:544667
|
| Nucleutide sequences |
EMBL-CDS:
AAI63921.1
Ensembl_TRS:
ENSDART00000187518,
ENSDART00000025621,
ENSDART00000130446
|
| Protein sequencees |
Ensembl_PRO:
ENSDARP00000002466,
ENSDARP00000157030,
ENSDARP00000106307
RefSeq:
NP_001014829.3,
NP_001244082.1
|
| Others |
UniRef100:
UniRef100_B3DKP1,
UniRef100_F1QBD0
UniRef90:
UniRef90_A4QNT7,
UniRef90_B3DKP1
UniRef50:
UniRef50_B3DKP1,
UniRef50_A4QNT7
UniGene:
Dr.87605
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员