| Type | Description |
|---|---|
| Definition | ETAA1 activator of ATR kinase |
| Date | Results | Publications |
|---|---|---|
| 2020-06-06 11:22:00 | ETAA1 may have an important role in protecting against genome instability arising from incompletely duplicated DNA via regulatory control of its ATR-stimulating potential | 31615875 |
| 2020-04-18 12:10:00 | ETAA1 regulates mitotic ATR signaling and is required for proper chromosome alignment during metaphase and for a fully functional spindle assembly checkpoint response. | 30755469 |
| 2019-12-14 10:18:00 | ETAA1 and TOPBP1 contain a predicted coiled-coil motif that is required for ATR activation in vitro and in cells. Mutation of the predicted coiled coils does not alter AAD oligomerization but does impair binding of the AADs to ATR. | 30940728 |
| 2018-01-27 10:43:00 | These our data suggest that ETAA1 is a new ATR activator involved in replication checkpoint control. | 27818175 |
| 2017-05-27 12:08:00 | results reveal that ETAA1 is a novel RPA-interacting protein that promotes restart of stalled replication forks. | 27601467 |
| Type | IDs |
|---|---|
| Synonymous | ETAA16 |
| Gene |
UniProtKB-ID:
ETAA1_HUMAN
UniprotKB:
Q9NY74
UniParc:
UPI00001414BC
EMBL:
AJ242682,
BC033075,
BC040001,
AC023668
Ensembl:
ENSG00000143971
KO:
hsa:54465
|
| Nucleutide sequences |
EMBL-CDS:
AAH33075.1,
AAX93100.1,
CAB76378.2,
AAH40001.1
Ensembl_TRS:
ENST00000272342
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000272342
RefSeq:
NP_061875.2,
XP_016859865.1,
XP_016859866.1
|
| Others |
UniRef100:
UniRef100_Q9NY74
UniRef90:
UniRef90_Q9NY74
UniRef50:
UniRef50_Q9NY74
UniGene:
Hs.353022
CCDS:
CCDS1882.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员