| Type | Description |
|---|---|
| Definition | F-box protein 42 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-02 12:51:00 | A genome-wide CRISPR screen identifies FBXO42 involvement in resistance toward MEK inhibition in NRAS-mutant melanoma. | 31549767 |
| 2015-10-10 11:51:00 | SCF(JFK) as a bona fide E3 ligase for ING4 and unraveled the JFK-ING4-NF-kappaB axis as an important player in the development and progression of breast cancer | 25792601 |
| 2014-04-05 13:44:00 | The findings of this study suggest that a haplotype of the FBXO42 gene might be associated with a higher susceptibility to PD. | 24063688 |
| 2011-03-26 10:46:00 | Substrate phosphorylation and feedback regulation in JFK-promoted p53 destabilization. | 21127074 |
| 2010-01-21 00:00:00 | JFK promotes p53 turnover through assembly of an SCF (Skp1-Cul1-F-box) complex, revealing a pathway for the control of p53 degradation and providing a link between the SCF complex and p53 regulation. | 19509332 |
| Type | IDs |
|---|---|
| Synonymous | Fbx42, JFK |
| Gene |
UniProtKB-ID:
FBX42_HUMAN
UniprotKB:
Q6P3S6
UniParc:
UPI0000161A51
EMBL:
AL109627,
AK055598,
BC006174,
BC043410,
AB037753,
AL358794,
BC032439,
AL833874,
BC063864
Ensembl:
ENSG00000037637
KO:
hsa:54455
|
| Nucleutide sequences |
EMBL-CDS:
AAH32439.1,
AAH63864.1,
BAG51542.1,
BAA92570.1,
CAD38731.1,
AAH06174.1,
AAH43410.1
Ensembl_TRS:
ENST00000375592
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000364742
RefSeq:
NP_061867.1,
XP_006710761.1,
XP_016856992.1,
XP_016856991.1
|
| Others |
UniRef100:
UniRef100_Q6P3S6
UniRef90:
UniRef90_Q6P3S6
UniRef50:
UniRef50_Q6P3S6
UniGene:
Hs.522384
CCDS:
CCDS30613.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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