| Type | Description |
|---|---|
| Definition | unc-93 homolog B1, TLR signaling regulator |
| Date | Results | Publications |
|---|---|---|
| 2020-04-11 12:34:00 | Binding of syntenin-1 requires phosphorylation of UNC93B1 and provides a mechanism for dynamic regulation of TLR7 activation and signalling | 31546246 |
| 2020-04-11 12:34:00 | Whereas TLR9 and TLR3 are released from UNC93B1, TLR7 does not dissociate from UNC93B1 in endosomes and is regulated by distinct mechanisms | 31546247 |
| 2019-02-02 12:06:00 | Data show that Unc-93 homolog B1 (UNC93B1) is critical for maintaining Toll-like receptors (TLRs) expression. | 29768176 |
| 2017-12-02 10:58:00 | autoantibody production in systemic mercury-induced autoimmunity was dependent on the endosomal TLR transporter UNC93B1 | 29055005 |
| 2017-08-26 11:12:00 | Autophagy contributes to macrophage resistance to Leishmania major. Data, including data from studies in knockout mice, suggest a key resistance mechanism involves endosomal signaling via Tlr3/7/9 in macrophages; macrophages deficient for Tlr3/7/9, Unc93b1, or MyD88 fail to undergo L. major-induced autophagy. (TLR = Toll-like receptor; Unc93b1 = unc-93 homolog B1; MyD88 = myeloid differentiation primary response gene 88) | 28607148 |
| Type | IDs |
|---|---|
| Synonymous | Unc-93B1, Unc93b |
| Gene |
UniProtKB-ID:
UN93B_MOUSE,
E9PYK0_MOUSE,
E9Q8P6_MOUSE
UniprotKB:
Q8VCW4,
E9PYK0,
E9Q8P6
UniParc:
UPI000217CB70,
UPI0001A52027,
UPI00000250A4,
UPI0001A52026
EMBL:
AC133523,
AJ422144,
AK165060,
BC023731,
U89424,
BC025587,
BC018388
Ensembl:
ENSMUSG00000036908
KO:
mmu:54445
|
| Nucleutide sequences |
EMBL-CDS:
AAH18388.1,
AAH23731.1,
AAH25587.1,
AAC36530.1,
CAD19524.1,
BAE38019.1
Ensembl_TRS:
ENSMUST00000162708,
ENSMUST00000165711
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000124272,
ENSMUSP00000128751
RefSeq:
NP_001154900.1,
NP_062322.2,
XP_006531861.1
|
| Others |
UniRef100:
UniRef100_E9Q8P6,
UniRef100_Q8VCW4
UniRef90:
UniRef90_Q8VCW4,
UniRef90_I3MHF9
UniRef50:
UniRef50_Q8VCW4,
UniRef50_I3MHF9
UniGene:
Mm.262094
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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