| Type | Description |
|---|---|
| Definition | potassium channel tetramerization domain containing 5 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-23 12:57:00 | KCTD5, a novel TRPM4-regulatory protein required for cell migration as a new predictor for breast cancer prognosis. | 32301552 |
| 2019-06-29 12:07:00 | Cullin3/KCTD5 downregulates the DNA-binding affinity of DeltaNp63alpha, impairing either its transactivity or its transinhibitory activity. Functionally, Cullin3/KCTD5 abates the proproliferation activity of DeltaNp63alpha. These findings suggest that KCTD5-based CRL3 may mediate monoubiquitination and is a novel regulator of DeltaNp63alpha. | 29782646 |
| 2017-10-21 10:54:00 | genetic modifier screen exposes suppressors of the KCTD5 phenotype and mechanistically demonstrates that KCTD5 acts as an off-switch for GPCR signalling by triggering proteolysis of Gbetagamma heterodimers dissociated from the Galpha subunit | 28562590 |
| 2015-11-14 11:29:00 | Identification of MCM7, ZNF711 and FAM193 as KCTD5 interaction partners.KCTD5 is not involved in polyubiquitylation of MCM7 replication factor.The KCTD5/cullin3 complex stabilizes ZNF711 transcription factor. | 26188516 |
| 2010-01-21 00:00:00 | we have identified a novel cellular AAV-2 Rep78/Rep68 interaction partner, KCTD5, located predominantly in the cytoplasm. | 17239418 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
KCTD5_HUMAN
UniprotKB:
Q9NXV2
UniParc:
UPI0000073110
EMBL:
BC007314,
AK000047,
CH471112
Ensembl:
ENSG00000167977
KO:
hsa:54442
|
| Nucleutide sequences |
EMBL-CDS:
EAW85489.1,
AAH07314.1,
BAA90906.1,
EAW85491.1
Ensembl_TRS:
ENST00000301738
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000301738
RefSeq:
NP_061865.1
|
| Others |
UniRef100:
UniRef100_Q9NXV2
UniRef90:
UniRef90_Q9NXV2
UniRef50:
UniRef50_Q9NXV2
UniGene:
Hs.61960
CCDS:
CCDS10475.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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