| Type | Description |
|---|---|
| Definition | RNA polymerase mitochondrial |
| Date | Results | Publications |
|---|---|---|
| 2021-04-03 13:37:00 | POLRMT mutations impair mitochondrial transcription causing neurological disease. | 33602924 |
| 2017-06-24 11:24:00 | the frequency of variation in sequence identity and length at conserved sequence block 2 amongst human mitochondrial genomes and used in vitro transcription to assess the effects of this length heterogeneity on the activity of the mitochondrial RNA polymerase, POLRMT, was examined. | 27436287 |
| 2016-09-10 11:03:00 | Suggest targeting POLRMT as strategy for treating acute myeloid leukemia. | 26484416 |
| 2016-05-21 12:59:00 | knock-down of MRPL12 by RNA interference results in instability of POLRMT. | 26586915 |
| 2016-03-19 11:18:00 | Results show that polymorphisms at POLG2 and POLRMT increased risk of oral cancer and leukoplakia, respectively, probably modulating synthesis and activity of the enzymes. | 26403317 |
| Type | IDs |
|---|---|
| Synonymous | APOLMT, MTRNAP, MTRPOL, h-mtRPOL |
| Gene |
UniProtKB-ID:
RPOM_HUMAN,
Q4G0F4_HUMAN
UniprotKB:
O00411,
Q4G0F4
UniParc:
UPI000013C68E,
UPI000056D4B7
EMBL:
BC098387,
AC004449,
U75370
Ensembl:
ENSG00000099821
KO:
hsa:5442
|
| Nucleutide sequences |
EMBL-CDS:
AAC06147.1,
AAB58255.1,
AAH98387.1
Ensembl_TRS:
ENST00000588649
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000465759
RefSeq:
XP_005259637.3,
NP_005026.3
|
| Others |
UniRef100:
UniRef100_O00411,
UniRef100_Q4G0F4
UniRef90:
UniRef90_O00411
UniRef50:
UniRef50_O00411
UniGene:
Hs.254113
CCDS:
CCDS12036.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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