| Type | Description |
|---|---|
| Definition | ATPase, H+ transporting, lysosomal accessory protein 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-11-21 13:31:00 | V-ATPase a3 isoform mutations identified in osteopetrosis patients abolish its expression and disrupt osteoclast function. | 32045577 |
| 2020-04-18 10:50:00 | Peptidylglycine alpha-amidating mono-oxygenase serves as a luminal pH-sensor, regulating V-ATPase action by altering its assembly status in peptidergic cells. | 30317586 |
| 2013-07-20 11:53:00 | The mitochondrial H(+)-ATP synthase, by coupling the Warburg effect to anabolic metabolism, enables de-differentiation during the reprogramming of somatic cells to induced pluripotent stem cells. | 23287468 |
| 2012-11-24 11:18:00 | The essential role of Ac45 in osteoclast-mediated extracellular acidification and protease exocytosis, as well as the ability of Ac45 to guide lysosomal intracellular trafficking to the ruffled border, is demonstrated. | 22467241 |
| 2012-05-19 10:47:00 | propose that, in addition to its canonical function in V-ATPase-mediated acidification, Ac45 plays versatile roles during osteoclast formation and function. | 22087256 |
| Type | IDs |
|---|---|
| Synonymous | 16A, AC45, AI316502, AW108110, Atp6ip1, Atp6s1, C7-1, CF2, VATPS1, XAP-3, mFLJ00383 |
| Gene |
UniProtKB-ID:
VAS1_MOUSE,
Q3UWN7_MOUSE,
Q3TWN7_MOUSE
UniprotKB:
Q9R1Q9,
Q3UWN7,
Q3TWN7
UniParc:
UPI000002167D,
UPI00005ABC6D
EMBL:
BC048241,
AK158956,
AK159612,
AL807376,
AB031290,
AK136210
Ensembl:
ENSMUSG00000019087
KO:
mmu:54411
|
| Nucleutide sequences |
EMBL-CDS:
AAH48241.1,
BAA83498.1,
BAE22877.1,
BAE35229.1,
CAM24343.1,
BAE34740.1
Gene_ORFName:
RP23-436K3.7-001
Ensembl_TRS:
ENSMUST00000019231
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000019231
RefSeq:
NP_061264.1,
NP_001345304.1,
NP_001345309.1,
XP_036017913.1
|
| Others |
UniRef100:
UniRef100_Q9R1Q9
UniRef90:
UniRef90_Q9R1Q9
UniRef50:
UniRef50_Q15904
UniGene:
Mm.21961
CCDS:
CCDS30226.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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