| Type | Description |
|---|---|
| Definition | receptor (calcitonin) activity modifying protein 2 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-17 13:14:00 | Adrenomedullin-Receptor Activity-Modifying Protein 2 System Ameliorates Subretinal Fibrosis by Suppressing Epithelial-Mesenchymal Transition in Age-Related Macular Degeneration. | 33385343 |
| 2019-10-26 11:48:00 | Development of a Novel Model of Central Retinal Vascular Occlusion and the Therapeutic Potential of the Adrenomedullin-Receptor Activity-Modifying Protein 2 System. | 30658846 |
| 2017-12-02 10:59:00 | the cardiovascular response of Ramp1(-/-), Ramp2(+/-), Ramp3(-/-), Ramp1(-/-)/Ramp3(-/-) double-knockout (dKO), and Calcrl(+/-) mice to AM and CGRP were compared to wildtype mice.These results suggest that the hypotensive effect of AM is primarily mediated through the CLR/RAMP1 heterodimer, but that AM signaling via CLR/RAMP2 and CLR/RAMP3 also contributes to some hypotensive action. | 27940069 |
| 2017-10-14 10:46:00 | The AM-RAMP2 system exerts crucial vasoprotective effects after vascular injury and could be a therapeutic target for the treatment of vascular diseases. | 28324104 |
| 2017-09-30 11:31:00 | Results provide in vivo evidence of a role for RAMP2 in placental development distinct from the RAMP2-calcitonin receptor-like receptor/adrenomedullin signaling paradigm; decreases Pthr1 expression and causes a blunted response to systemic parathyroid hormone; and identify additional pathways underlying the endocrine and fertility defects of the previously characterized Ramp2 heterozygous adult females. | 28727763 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
RAMP2_MOUSE
UniprotKB:
Q9WUP0
UniParc:
UPI0000020B4E
EMBL:
AK003810,
AF146523,
AJ250490,
BC069992,
AF209906
Ensembl:
ENSMUSG00000001240
KO:
mmu:54409
|
| Nucleutide sequences |
EMBL-CDS:
AAF21038.1,
AAD35019.1,
CAB59512.1,
AAH69992.1,
BAB23009.1
Ensembl_TRS:
ENSMUST00000129680
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000122072
RefSeq:
NP_062317.1
|
| Others |
UniRef100:
UniRef100_Q9WUP0
UniRef90:
UniRef90_Q9WUP0
UniRef50:
UniRef50_Q9WUP0
UniGene:
Mm.260698,
Mm.298256
CCDS:
CCDS25457.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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