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54407 SLC38A2

54407

SLC38A2

solute carrier family 38 member 2

protein-coding

Homo sapiens

基因描述

Type Description
Definition solute carrier family 38 member 2

研究结论

Date Results Publications
2021-04-17 13:11:00 Increased expression of glutamine transporter SNAT2/SLC38A2 promotes glutamine dependence and oxidative stress resistance, and is associated with worse prognosis in triple-negative breast cancer. 33028955
2020-12-05 12:58:00 Functional Consequences of Low Activity of Transport System A for Neutral in Human Bone Marrow 32164327
2020-07-18 11:50:00 We describe how Slc38a2 senses amino acid availability and passes this onto intracellular signaling pathways and how it regulates protein synthesis, cellular proliferation and apoptosis through the mechanistic (mammalian) target of rapamycin (mTOR) and general control nonderepressible 2 (GCN2) pathways--{REVIEW} 31574264
2020-04-11 12:16:00 findings show a switch in the regulation of SNAT2 between ERalpha and HIF-1alpha, leading to endocrine resistance in hypoxia 31152137
2019-06-23 00:18:00 nutrient ingestion during repeated 30-s bouts of sprint exercise induces expression of the amino acid transporter SNAT2 and stimulates Akt/mTOR signaling and most likely the rate of muscle protein synthesis 28860165

名称对应

Type IDs
Synonymous ATA2, PRO1068, SAT2, SNAT2
Gene
UniProtKB-ID: S38A2_HUMAN, A0A024R0W3_HUMAN, Q8NHT5_HUMAN
UniprotKB: Q96QD8, A0A024R0W3, Q8NHT5
UniParc: UPI000006EA11, UPI000037842A, UPI000000121A
EMBL: CR457267, BC029379, AK001700, AK172784, AF298897, AJ344099, AB037803, CH471111, AF259799, BC040342
Ensembl: ENSG00000134294
KO: hsa:54407
Nucleutide sequences
EMBL-CDS: EAW57901.1, AAH40342.1, AAG24618.1, CAC51434.1, EAW57900.1, CAG33548.1, BAA92620.2, AAK38510.1, BAD18765.1, BAA91846.1, EAW57902.1, AAH29379.1
Gene_ORFName: hCG_39510
Ensembl_TRS: ENST00000256689, ENST00000612232
Protein sequencees
Ensembl_PRO: ENSP00000482873, ENSP00000256689
RefSeq: NP_061849.2, NP_001294865.1
Others
UniRef100: UniRef100_Q8NHT5, UniRef100_Q96QD8
UniRef90: UniRef90_Q96QD8, UniRef90_Q8NHT5
UniRef50: UniRef50_Q8NHT5, UniRef50_Q9JHE5
UniGene: Hs.221847
CCDS: CCDS8749.1, CCDS76551.1

全选

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