| Type | Description |
|---|---|
| Definition | Iroquois homeobox 5 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-13 10:08:00 | IRX3/5 regulate mitotic chromatid segregation and limb bud shape. | 32907847 |
| 2020-10-31 13:16:00 | Canonical Wnt/beta-catenin activity and differential epigenetic marks direct sexually dimorphic regulation of Irx3 and Irx5 in developing mouse gonads. | 32108023 |
| 2020-06-06 13:19:00 | Studied role of Iroquois homeobox 5 (Irx5) in adipocytes, amyloid precursor protein, and mitochondrial respiration in obesity mouse models and patients. | 30538277 |
| 2019-12-21 10:17:00 | Promotion of IRX3 signalling or inhibition of IRX5 signalling could be a route towards differentiation therapy for Wilms tumour, in which WNT5A is a candidate molecule for enforced tubular maturation. | 30246301 |
| 2019-01-19 12:19:00 | Irx3 and Irx5 first work together to define the pregranulosa cell population of germline nests. During primordial follicle formation, they transition to oocyte- and granulosa cell-specific expression patterns where they cooperate in neighboring cells to build the foundation for follicle integrity. | 30071018 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
IRX5_MOUSE
UniprotKB:
Q9JKQ4
UniParc:
UPI0000023879
EMBL:
AK004747,
AF165985,
BC056994,
AF230074,
BC051959
Ensembl:
ENSMUSG00000031737
KO:
mmu:54352
|
| Nucleutide sequences |
EMBL-CDS:
AAH51959.2,
AAH56994.1,
AAF63955.1,
AAF42871.1,
BAB23528.1
Ensembl_TRS:
ENSMUST00000034184
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000034184
RefSeq:
NP_061296.1
|
| Others |
UniRef100:
UniRef100_Q9JKQ4
UniRef90:
UniRef90_Q9JKQ4
UniRef50:
UniRef50_P78411
UniGene:
Mm.101153
CCDS:
CCDS22522.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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