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5431 POLR2B

5431

POLR2B

RNA polymerase II subunit B

protein-coding

Homo sapiens

基因描述

Type Description
Definition RNA polymerase II subunit B

研究结论

Date Results Publications
2011-03-05 10:42:00 Studies indicate transcription of many genes, is regulated after the initiation step, by pausing of RNA polymerase II during elongation through the promoter-proximal region. 21081187
2010-06-30 22:06:00 Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) 20379614
2010-01-21 00:00:00 By reducing transcriptional fidelity in terms of not only discrimination of incoming nucleotides but also recognition of templates, HDAg may facilitate the unusual RNA-dependent RNA synthesis by Pol II. 17584298
2010-01-21 00:00:00 The highly conserved glutamic acid 791 of Rpb2 is involved in the binding of magnesium and is required for both for the polymerization and cleavage reactions. 15886393
2010-01-21 00:00:00 the human Maf1 protein negatively regulates transcription by all three nuclear Pols, Pol I, Pol II and Pol III 17499043

名称对应

Type IDs
Synonymous POL2RB, RPB2, hRPB140
Gene
UniProtKB-ID: RPB2_HUMAN, C9J2Y9_HUMAN, B4DHJ3_HUMAN, B4DH29_HUMAN
UniprotKB: P30876, C9J2Y9, B4DHJ3, B4DH29
UniParc: UPI00017A7240, UPI00017A6FA7, UPI00001345D1, UPI0000074177
EMBL: BC023503, AF055028, X63563, AK295132, CH471057, AK294901, AK289823, AC069307
Ensembl: ENSG00000047315
KO: hsa:5431
Nucleutide sequences
EMBL-CDS: EAX05519.1, BAF82512.1, AAH23503.2, AAC09367.1, CAA45124.1, BAG58155.1, BAG57990.1
Ensembl_TRS: ENST00000314595, ENST00000381227, ENST00000441246
Protein sequencees
Ensembl_PRO: ENSP00000312735, ENSP00000370625, ENSP00000391452
RefSeq: NP_001290198.1, NP_001290197.1, NP_000929.1
Others
UniRef100: UniRef100_P30876, UniRef100_B4DH29, UniRef100_B4DHJ3
UniRef90: UniRef90_B4DHJ3, UniRef90_B4DH29, UniRef90_P30876
UniRef50: UniRef50_P30876, UniRef50_Q8CFI7
UniGene: Hs.602757
CCDS: CCDS3511.1

全选

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研究热度

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