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54300 Slc12a3

54300

Slc12a3

solute carrier family 12 member 3

protein-coding

Rattus norvegicus

基因描述

Type Description
Definition solute carrier family 12 member 3

研究结论

Date Results Publications
2019-07-13 11:40:00 Kidney-specific WNK1 isoform is a potent activator of WNK4 and NCC-mediated sodium/chloride transport. 29846116
2019-07-13 11:24:00 The presence of active plasmin in urine in hydronephrosis could cause abnormal proteolytic activation of ENaC-gamma and impaired ability to excrete Na via NCC. 29767556
2017-09-23 10:07:00 Kidneys respond acutely to hyperkalemic challenges by decreasing the activity of NCC while increasing that of ENaC. 28356292
2017-07-15 12:10:00 Direct epithelial action of calcineurin inhibitor cyclosporine A is sufficient for the activation of renal NCC. 28003191
2016-05-07 10:23:00 Data demonstrate that increased levels of NE prevent dietary sodium-evoked suppression of the NCC, via an ANG II-independent mechanism, to stimulate the development of salt-sensitive hypertension. 26608659

名称对应

Type IDs
Synonymous NCC, TSC
Gene
UniProtKB-ID: S12A3_RAT, G3V8G0_RAT
UniprotKB: P55018, G3V8G0
UniParc: UPI000013541F, UPI0000250ED5
EMBL: CH474006, U10097, AABR07042830, AABR07042831
Ensembl: ENSRNOG00000057072
KO: rno:54300
Nucleutide sequences
EMBL-CDS: AAA21252.2, EDL87346.1
Gene_ORFName: rCG_39020
Ensembl_TRS: ENSRNOT00000081246
Protein sequencees
Ensembl_PRO: ENSRNOP00000070064
RefSeq: XP_008770545.1, XP_008770546.1, XP_008770550.1, NP_062218.3, XP_008770549.1, XP_008770547.1, XP_008770548.1
Others
UniRef100: UniRef100_G3V8G0, UniRef100_P55018
UniRef90: UniRef90_P59158
UniRef50: UniRef50_P59158
UniGene: Rn.10467

全选

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研究热度

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